J Korean Neurol Assoc.
2023 Nov;41(4):314-317. 10.17340/jkna.2023.0034.
Two Cases of Perinuclear Anti-neutrophil Cytoplastic Antibodies Associated Hypertrophic Pachymeningitis Presented with Visual Loss
- Affiliations
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- 1Department of Neurology, Seoul National University Bundang Hospital, Seongnam, Korea
- 2Department of Neurology, Seoul National University College of Medicine, Seoul, Korea
- KMID: 2547621
- DOI: http://doi.org/10.17340/jkna.2023.0034
Abstract
- Pachymeningitis is an inflammatory process mainly involving the dura mater and is possibly associated with infectious, neoplastic, or autoimmune disease. However, in most cases, the etiology remains unknown. Clinical manifestations of pachymeningitis can vary, ranging from headache, cranial neuropathy, cerebellar dysfunction, to seizure. Here we report two cases of perinuclear anti-neutrophil cytoplasmic antibodies associated with pachymeningitis, in both the visual loss attributed to optic neuropathy was the primary sign.
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