J Vet Sci.  2023 Sep;24(5):e64. 10.4142/jvs.23124.

Metastatic intestinal adenocarcinoma with osseous metaplasia in two Domestic Korean Shorthair cats

Affiliations
  • 1Laboratory of Clinical Pathology, College of Veterinary Medicine, Seoul National University, Seoul 08826, Korea
  • 2BK 21 PLUS Program for Creative Veterinary Science Research, College of Veterinary Medicine, Seoul National University, Seoul 08826, Korea
  • 3Eum Animal Medical Center, Hwaseong 18501, Korea
  • 4Top Care Animal Medical Center, Goyang 10500, Korea
  • 5PATH Inc., Seoul 05734, Korea
  • 6Research Institute for Veterinary Science, College of Veterinary Medicine, Seoul National University, Seoul 08826, Korea

Abstract

Two Domestic Korean Shorthair cats presented with dyschezia and vomiting. Computed tomography revealed a colonic mass with calcification and lymph node metastasis in case 1, and a small intestinal mass with disseminated mesenteric metastasis and calcification in case 2. Histopathology revealed intestinal adenocarcinoma with osseous metaplasia. Case 1 died two months after surgery from distant metastasis; and case 2 showed no metastasis for five months but presented with anorexia, euthanized seven months after diagnosis. Metastatic intestinal adenocarcinoma with bone formation should be considered as differential diagnosis for calcification on imaging, and lymph node metastasis at diagnosis may indicate poor prognosis.

Keyword

Case reports; intestinal neoplasms; metastasis; ossification; cat
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