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Osseous metaplasia is defined as the formation of lamellar bone inside soft tissue structures where bone normally does not exist. It results from the transformation of non-osseous connective tissue into mature bone. This condition is rare in the oral and maxillofacial region. We report a case of osseous metaplasia of the maxilla, a rare benign tumor in an uncommon region. A 60-year-old male patient visited our clinic complaining of foreign body sensation and asymptomatic swelling on the right palatal side. However, he did not experience pain and reported no local trauma that he could remember. Intra-oral examination revealed an exophytic lesion on the right palatal portion. On computed tomography, there was a round hard-tissue mass approximately 2 cm in diameter on the right palate area. The mass was biopsied and diagnosed as an osseous metaplasia. We review the clinical, radiographic, and histologic features and common causes of osseous metaplasia and report a rare case of osseous metaplasia of the palate.
Fig. 1
Computed tomography image showing a round, hard-tissue mass approximately 2 cm in diameter. A. Axial view. B. Coronal view.
Fig. 2
Histopathologic images of the excised osseous mass (H&E staining, A: ×12.5, B: ×200). A. Microphotograph at low-power view reveals a well-circumscribed bone mass composed of irregular bone trabeculae and fatty marrow. B. Higher magnification of osseous metaplasia showing woven bone trabeculae with prominent osteoblasts.
5. Maitra S, Gupta D, Radojkovic M, Sood S. 2009; Osseous metaplasia of the maxillary sinus with formation of a well-developed haversian system and bone marrow. Ear Nose Throat J. 88:1115–20. DOI: 10.1177/014556130908800907. PMID: 19750475. Article