Lab Med Qual Assur.  2023 Sep;45(3):115-119. 10.15263/jlmqa.2023.45.3.115.

Analysis of Unacceptable Results in Proficiency Testing for General Transfusion Medicine Tests

• Kim HJ
• Chung Y
• Kim H
• Hwang SH
• Oh HB
• Ko DH

• KMID: 2546624
• DOI: http://doi.org/10.15263/jlmqa.2023.45.3.115

Abstract

Background
External quality assessment (EQA) in transfusion medicine is conducted by the Korean Association of External Quality Assessment Service (KEQAS) for five programs covering 14 survey items. Results were annually analyzed and published in Laboratory Medicine and Quality Assurance, the official academic journal of KEQAS. Identifying trends in the transfusion medicine program is challenging due to remarkably low error rate. We aimed to analyze the error rates and types across recent 4-year results of general blood transfusion tests and suggest applicable solutions for laboratories.
Methods
The results and reports from participating laboratories in general blood transfusion tests of the EQA between 2019–2022 were analyzed. Specifically, we categorized the ‘unacceptable’ results and analyzed their patterns. Statistical analysis was performed using R ver. 4.0.0.
Results
A total of 6,277 reports with 193,152 results were analyzed. A total of 4,681 results were unacceptable. There were between 549–768 unacceptable results per round, with an average of 2.4%. Among them, majority (4,159 cases, 88.8%) of the results were attributed to incorrect interpretation of agglutination. When categorized by survey item, there was a significantly higher number of errors in interpreting agglutination in serum typing of an ABO group than in cell typing. Analyzing the error type by each year, agglutination interpretation error was the most frequent. Errors due to differences in test methods tend to be relatively decreasing.
Conclusions
Accurate interpretation of the test results, careful consideration for selection of test methods, and cross-validation to minimize clerical errors are necessary. Additionally, continuous education and making efforts towards improvements are essential.

Keyword

Background: External quality assessment (EQA) in transfusion medicine is conducted by the Korean Association of External Quality Assessment Service (KEQAS) for five programs covering 14 survey items.; Quality improvement; Laboratory proficiency testing