Clin Endosc.  2023 Sep;56(5):677-679. 10.5946/ce.2023.078.

Unusual cause of persistent chest pain

• Kim Y
• Ahn JY

• KMID: 2546148
• DOI: http://doi.org/10.5946/ce.2023.078

Figure

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  Fig. 1. Endoscopic image of the esophageal mass. Esophagogastroduodenoscopy reveals a large ulceroinfiltrative mass occupying two-thirds of the esophageal lumen. Black mucosal pigmentation is observed around the mass.

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  Fig. 2. Coronal view of F-18 fluorodeoxyglucose positron emission tomography-computed tomography. A diffuse hypermetabolic mass is visible in the midthoracic esophagus. Multiple hypermetabolic lymph nodes are visible in the mediastinal, right upper paratracheal, upper paratracheal, and retroperitoneal regions.

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  Fig. 3. Histopathologic finding of the esophageal mass. (A) Hematoxylin and eosin stain of the esophageal biopsy shows numerous black pigmented cells (×20). (B) Immunohistochemistry staining showing HMB-45 and S-100 positivities. P40 is weakly positive, while cytokeratin (CK) is negative (×10).

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