J Korean Ophthalmol Soc.  2023 Aug;64(8):754-758. 10.3341/jkos.2023.64.8.754.

Probable Posterior Ischemic Optic Neuropathy Associated with Acute Fungal Sinusitis

Affiliations
  • 1Department of Ophthalmology, Pusan National University Yangsan Hospital, Pusan National University School of Medicine, Yangsan, Korea
  • 2Research Institute for Convergence of Biomediocal Science and Technology, Pusan National University Yangsan Hospital, Yangsan, Korea

Abstract

Purpose
We report a case of probable posterior ischemic optic neuropathy in a patient with acute fungal sinusitis.
Case Summary
An 81-year-old male patient presented with sudden-onset visual loss in his left eye 3 weeks prior to presentation. His best corrected visual acuity was 0.6 in his right eye and light perception in his left eye. Pupillary size was 3 mm in both eyes, and a relative afferent pupillary defect was detected in his left eye. In fundus examination, diabetic retinopathy was found, and cup/disc ratios were increased in both eyes, but disc swelling and hemorrhage were not observed. Fluorescein angiography did not indicate filling delay, defects, or leakage of discs in either eye. Magnetic resonance imaging of the brain revealed multi-sinusitis in the sphenoid, ethmoid, and frontal sinuses. No bony defects or erosion were found around the optic canal or orbital apex during endoscopic surgery; however, histological examination revealed aspergillosis. The patient was diagnosed with posterior ischemic optic neuropathy caused by acute fungal sinusitis.
Conclusions
When elderly patients with uncontrolled diabetes experience sudden visual disturbances without ocular pain, posterior ischemic optic neuropathy with fungal sinusitis should be considered as a differential diagnosis. Immediate imaging studies and appropriate treatment should be performed.

Keyword

Aspergillosis, Fungal sinusitis, Posterior ischemic optic neuropathy
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