Korean J Dermatol.  2023 Jul;61(6):374-377.

A Case of Desmoplastic Spitz Nevus with Pseudo-Gland Formation

Affiliations
  • 1Departments of Dermatology, Ilsan Paik Hospital, Inje University College of Medicine, Goyang, Korea
  • 2Departments of Pathology, Ilsan Paik Hospital, Inje University College of Medicine, Goyang, Korea

Abstract

Desmoplastic Spitz nevus is a rare variant of Spitz nevus characterized by predominantly spindle-shaped or epithelioid nevus cells within the fibrotic stroma that can be confused with fibrous lesions. A 43-year-old woman presented with a 1-cm-sized dome-shaped papule on the dorsum of her left foot. The lesion showed histopathological features of a desmoplastic Spitz nevus with structures that resemble adenoma. Immunohistochemical staining was positive for S-100 protein, Melan-A, and SOX-10. Herein, we report this case because desmoplastic Spitz nevus is rare and can lead to confusion regarding the diagnosis of adnexal neoplasms.

Keyword

Desmoplastic; Epitheloid and spindle cell nevus
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