Clin Mol Hepatol.  2023 Jul;29(3):521-541. 10.3350/cmh.2023.0202.

Transarterial chemoembolization for hepatocellular carcinoma: 2023 Expert consensus-based practical recommendations of the Korean Liver Cancer Association

Affiliations
  • 1Center for Liver and Pancreatobiliary Cancer, National Cancer Center, Goyang, Korea
  • 2Department of Radiology, Seoul National University Hospital, Seoul, Korea
  • 3Department of Radiology, Pusan National University Hospital, Busan, Korea
  • 4Department of Radiology, Jeonbuk National University Hospital, Jeonju, Korea
  • 5Department of Radiology, Chonnam National University Hwasun Hospital, Chonnam National University Medical School, Hwasun, Korea
  • 6Department of Radiology, Chonnam National University Hwasun Hospital, Chonnam National University Medical School, Hwasun, Korea
  • 7Department of Internal Medicine, Seoul Metropolitan Government Seoul National University Boramae Medical Center, Seoul, Korea
  • 8Department of Internal Medicine, Ewha Womans University College of Medicine, Seoul, Korea
  • 9Department of Radiology, Yonsei University College of Medicine, Seoul, Korea
  • 10Department of Radiology, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea
  • 11Department of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
  • 12Department of Radiology, National Cancer Center, Goyang, Korea

Abstract

Transarterial chemoembolization (TACE) was introduced in 1977 with the administration of chemotherapeutic agent to gelatin sponge particles through the hepatic artery in patients with hepatocellular carcinoma (HCC) and was established as conventional TACE using Lipiodol in the 1980s. In the 2000s, drug-eluting beads were developed and applied clinically. Currently, TACE is a commonly used non-surgical treatment modality for patients with HCC who are unsuitable for curative treatment. Considering the vital role of TACE in the management of HCC, it is crucial to organize current knowledge and expert opinions regarding patient preparation, procedural techniques, and post-treatment care in TACE, which can enhance therapeutic efficacy and safety. A group of 12 experts in the fields of interventional radiology and hepatology, convened by the Research Committee of the Korean Liver Cancer Association (KLCA), has developed expert consensus-based practical recommendations in TACE. These recommendations have been endorsed by the Korean Society of Interventional Radiology and provide useful information and direction in performing TACE procedure as well as pre- and post- procedural patient care.

Keyword

Hepatocellular carcinoma; Chemoembolization; Recommendations; Guidance; Guideline
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