Nucl Med Mol Imaging.  2023 Jun;57(3):155-158. 10.1007/s13139-022-00781-3.

Diagnosis of Fungal Infection (Candida albicans) After Heart Transplantation in a Pediatric Case with Fever of Unknown Origin: Role of 99mTc‑UBI SPECT/CT and 18F‑FDG PET/CT

Affiliations
  • 1Cardiovascular Interventional Research Center, Department of Nuclear Medicine, Rajaei Cardiovascular, Medical, and Research Center, Iran University of Medical Sciences, Tehran, Iran
  • 2Department of Nuclear Medicine, Hazrate Rasool Akram Hospital, Iran University of Medical Sciences, Tehran, Iran
  • 3Rajaie Cardiovascular Medical and Research Center, School of Medicine, Iran University of Medical Sciences, Tehran, Iran

Abstract

The diagnosis of patients with fever of unknown origin (FUO) in pediatric heart transplantation is a challenging medical problem. The physician should differentiate between rejections, infections, malignancy, adrenal insufficiency, and drug fever. Immunosuppressive therapy in these patients exposes them to a high risk of developing a post-transplantation fungal infection. In this case, we discuss the diagnostic contribution of the 99mTc-UBI scan and 18F-FDG PET scan for diagnosis of fungal infection causing FUO in these patients.

Keyword

FUO; Computed Tomography; Positron Emission Tomography; Fungal Infection
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