Nucl Med Mol Imaging.
2012 Jun;46(2):125-128.
A Case of Acute Q Fever Hepatitis Diagnosed by F-18 FDG PET/CT
- Affiliations
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- 1Department of Nuclear Medicine, Asan Medical Center, University of Ulsan College of Medicine, 86, Asanbyeongwon-gil, Songpa-gu, Seoul 138-736, Republic of Korea. jsryu2@amc.seoul.kr
- 2Department of Radiology, Kangdong Seong-Sim Hospital, Hallym University College of Medicine, 150, Sungan-ro, Kangdong-gu, Seoul 134-701, Republic of Korea.
- 3Department of Infectious Diseases, Asan Medical Center, University of Ulsan College of Medicine, 86, Asanbyeongwon-gil, Songpa-gu, Seoul 138-736, Republic of Korea.
- 4Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine, 86, Asanbyeongwon-gil, Songpa-gu, Seoul 138-736, Republic of Korea.
Abstract
- A 53-year-old man with fever of unknown origin underwent F-18 fluorodeoxyglucose positron emission tomography/computed tomography (F-18 FDG PET/CT) as a workup for a fever of unknown origin. On presentation, he complained of fever, chills, and myalgia. The F-18 FDG PET/CT scan showed diffusely increased uptake of the liver with mild hepatomegaly. A liver biopsy then revealed fibrin-ring granulomas typically seen in Q fever. The patient was later serologically diagnosed as having acute Q fever as the titers for C. burnetii IgM and IgG were 64:1 and 16:1, respectively. He recovered completely following administration of doxycycline. This indicates that F-18 FDG PET/CT may be helpful for identifying hepatic involvement in Q fever as a cause of fever of unknown origin.
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