Korean J Sports Med.  2023 Jun;41(2):90-99. 10.5763/kjsm.2023.41.2.90.

The Effect of Intermittent Resistance Activity for Interrupting Prolonged Sitting on Vascular Function and Postprandial Metabolism after a High-fat Meal

• Cho MJ
• Jung YJ
• Kim YW
• Choi TG
• Kim JY
• Kim HJ
• Jae SY

• KMID: 2542980
• DOI: http://doi.org/10.5763/kjsm.2023.41.2.90

Abstract

Purpose
Numerous studies have reported the effects of interrupting prolonged sitting with aerobic exercise on vascular and postprandial function, but the effects of resistance exercise for interrupting prolonged sitting remain unclear. We tested the hypothesis that intermittent resistance activity breaks would attenuate prolonged sittinginduced vascular and postprandial metabolic dysfunction.
Methods
Fourteen healthy adults (age, 24±2 years; body mass index, 22.0±2.4 kg/m² ) completed two trials in a randomized cross-over design. During a 4-hour sitting after a high-fat meal, the participants underwent either resistance activity (RA) with 10 repetitions of five exercises every hour or uninterrupted sitting as a control trial (SIT). Plasma glucose, triglycerides, and brachial artery blood pressure, along with blood flow and shear rate in the superficial femoral artery and carotid artery were measured at baseline and every hour during the 4-hour sitting period. Brachial artery flow-mediated dilation (FMD) was measured at baseline, 2 hours, and 4 hours after the start of the sitting.
Results
Plasma glucose and triglycerides increased after a high-fat meal in both RA and SIT groups without a significant interaction effect. In addition, while SIT group decreased brachial artery FMD (7.2%±2.0% to 6.5%±2.7% to 5.1%±2.6%), RA did not attenuate a decrease in FMD (7.6%±3.4% to 7.3%±3.1% to 6.7%±2.7%, interaction p=0.581).
Conclusion
Our findings indicate that interrupting prolonged sitting with intermittent RA did not attenuate the negative effects of sitting on vascular function and postprandial metabolism in young healthy adults.

Keyword

Sedentary behavior; Vasodilation; Resistance training; Regional blood flow; Postprandial period

Figure

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  Fig. 1 Experimental design.

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  Fig. 2 Comparison of changes in glucose (A) and triglycerides (B) after a high-fat meal between resistance activity trial (RA) and sitting trial (SIT). Data are mean±standard deviation.

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  Fig. 3 Comparison of change in brachial artery flow-mediated between resistance activity trial (RA) and sitting trial (SIT). Data are mean±standard deviation.

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