J Korean Neurosurg Soc.  2023 May;66(3):289-297. 10.3340/jkns.2022.0262.

The Long-Term Outcome and Rehabilitative Approach of Intraventricular Hemorrhage at Preterm Birth

Affiliations
  • 1Department and Research Institute of Rehabilitation Medicine, Yonsei University College of Medicine, Seoul, Korea

Abstract

Technological advances in neonatology led to the improvement of the survival rate in preterm babies with very low birth weights. However, intraventricular hemorrhage (IVH) has been one of the major complications of prematurity. IVH is relevant to neurodevelopmental disorders, such as cerebral palsy, language and cognitive impairments, and neurosensory and psychiatric problems, especially when combined with brain parenchymal injuries. Additionally, severe IVH requiring shunt insertion is associated with a higher risk of adverse neurodevelopmental outcomes. Multidisciplinary and longitudinal rehabilitation should be provided for these children based on the patients’ life cycles. During the infantile period, it is essential to detect high-risk infants based on neuromotor examinations and provide early intervention as soon as possible. As babies grow up, close monitoring of language and cognitive development is needed. Moreover, providing continuous rehabilitation with task-specific and intensive repetitive training could improve functional outcomes in children with mild-to-moderate disabilities. After school age, maintaining the level of physical activity and managing complications are also needed.

Keyword

Cerebral intraventricular hemorrhage; Premature birth; Neurodevelopmental disorders; Rehabilitation

Reference

References

1. Adams-Chapman I, Hansen NI, Stoll BJ, Higgins R; NICHD Research Network. Neurodevelopmental outcome of extremely low birth weight infants with posthemorrhagic hydrocephalus requiring shunt insertion. Pediatrics. 121:e1167–e1177. 2008.
Article
2. Adams-Chapman I, Heyne RJ, DeMauro SB, Duncan AF, Hintz SR, Pappas A, et al. Neurodevelopmental impairment among extremely preterm infants in the neonatal research network. Pediatrics. 141:e20173091. 2018.
Article
3. Ahn SY, Shim SY, Sung IK. Intraventricular hemorrhage and post hemorrhagic hydrocephalus among very-low-birth-weight infants in Korea. J Korean Med Sci. 30 Suppl 1(Suppl 1):S52–S58. 2015.
Article
4. Amen JF, El-Mikkawy DM, Yosry AH, El-Gebely MA, El-Sherbini MH. Outcome of intensive rehabilitation following single-event multilevel surgery for crouch gait in children with cerebral palsy. ERAR. 46:78–84. 2019.
Article
5. Ancel PY, Goffinet F; EPIPAGE-2 Writing Group, Kuhn P, Langer B, Matis J, et al. Survival and morbidity of preterm children born at 22 through 34 weeks’ gestation in france in 2011: results of the epipage-2 cohort study. JAMA Pediatr. 169:230–238. 2015.
6. Ancel PY, Livinec F, Larroque B, Marret S, Arnaud C, Pierrat V, et al. Cerebral palsy among very preterm children in relation to gestational age and neonatal ultrasound abnormalities: the epipage cohort study. Pediatrics. 117:828–835. 2006.
Article
7. Ann Wy P, Rettiganti M, Li J, Yap V, Barrett K, Whiteside-Mansell L, et al. Impact of intraventricular hemorrhage on cognitive and behavioral outcomes at 18 years of age in low birth weight preterm infants. J Perinatol. 35:511–515. 2015.
Article
8. Argyropoulou MI, Astrakas LG, Xydis VG, Drougia A, Mouka V, Goel I, et al. Is low-grade intraventricular hemorrhage in very preterm infants an innocent condition? Structural and functional evaluation of the brain reveals regional neurodevelopmental abnormalities. AJNR Am J Neuroradiol. 41:542–547. 2020.
Article
9. Ballabh P. Intraventricular hemorrhage in premature infants: mechanism of disease. Pediatr Res. 67:1–8. 2010.
Article
10. Ballabh P. Pathogenesis and prevention of intraventricular hemorrhage. Clin Perinatol. 41:47–67. 2014.
Article
11. Bassan H. Intracranial hemorrhage in the preterm infant: understanding it, preventing it. Clin Perinatol. 36:737–762. v, 2009.
Article
12. Bax M, Goldstein M, Rosenbaum P, Leviton A, Paneth N, Dan B, et al. Proposed definition and classification of cerebral palsy, april 2005. Dev Med Child Neurol. 47:571–576. 2005.
Article
13. Bjornson K, Hays R, Graubert C, Price R, Won F, McLaughlin JF, et al. Botulinum toxin for spasticity in children with cerebral palsy: a comprehensive evaluation. Pediatrics. 120:49–58. 2007.
Article
14. Blackman JA, Svensson CI, Marchand S. Pathophysiology of chronic pain in cerebral palsy: implications for pharmacological treatment and research. Dev Med Child Neurol. 60:861–865. 2018.
Article
15. Bosanquet M, Copeland L, Ware R, Boyd R. A systematic review of tests to predict cerebral palsy in young children. Dev Med Child Neurol. 55:418–426. 2013.
Article
16. Bruggink JL, Van Braeckel KN, Bos AF. The early motor repertoire of children born preterm is associated with intelligence at school age. Pediatrics. 125:e1356–e1363. 2010.
Article
17. Buffart LM, van den Berg-Emons RJ, van Wijlen-Hempel MS, Stam HJ, Roebroeck ME. Health-related physical fitness of adolescents and young adults with myelomeningocele. Eur J Appl Physiol. 103:181–188. 2008.
Article
18. Bulekbayeva S, Daribayev Z, Ospanova S, Vento S. Cerebral palsy: a multidisciplinary, integrated approach is essential. Lancet Glob Health. 5:e401. 2017.
Article
19. Butcher PR, van Braeckel K, Bouma A, Einspieler C, Stremmelaar EF, Bos AF. The quality of preterm infants’ spontaneous movements: an early indicator of intelligence and behaviour at school age. J Child Psychol Psychiatry. 50:920–930. 2009.
Article
20. Capute AJ, Accardo PJ. The infant neurodevelopmental assessment: a clinical interpretive manual for cat-clams in the first two years of life, part 2. Curr Probl Pediatr. 26:279–306. 1996.
21. Carlon SL, Taylor NF, Dodd KJ, Shields N. Differences in habitual physical activity levels of young people with cerebral palsy and their typically developing peers: a systematic review. Disabil Rehabil. 35:647–655. 2013.
Article
22. Cavonius-Rintahaka D, Aho AL, Voutilainen A, Billstedt E, Gillberg C. Health, functionality, and social support in families with a child with a neurodevelopmental disorder - a pilot study. Neuropsychiatr Dis Treat. 15:1151–1161. 2019.
23. Cha JH, Ahn JH, Kim YJ, Lee BG, Kim JI, Park HK, et al. Impact of preterm birth on neurodevelopmental disorders in South Korea: a nationwide population-based study. J Clin Med. 11:2476. 2022.
Article
24. Choi JY, Yi SH, Ao L, Tang X, Xu X, Shim D, et al. Virtual reality rehabilitation in children with brain injury: a randomized controlled trial. Dev Med Child Neurol. 63:480–487. 2021.
Article
25. Chu SM, Tsai MH, Hwang FM, Hsu JF, Huang HR, Huang YS. The relationship between attention deficit hyperactivity disorder and premature infants in Taiwanese: a case control study. BMC Psychiatry. 12:85. 2012.
Article
26. Cieza A, Causey K, Kamenov K, Hanson SW, Chatterji S, Vos T. Global estimates of the need for rehabilitation based on the global burden of disease study 2019: a systematic analysis for the global burden of disease study 2019. Lancet. 396:2006–2017. 2021.
Article
27. Colver A, Rapp M, Eisemann N, Ehlinger V, Thyen U, Dickinson HO, et al. Self-reported quality of life of adolescents with cerebral palsy: a crosssectional and longitudinal analysis. Lancet. 385:705–716. 2015.
Article
28. Deng W, Pleasure J, Pleasure D. Progress in periventricular leukomalacia. Arch Neurol. 65:1291–1295. 2008.
Article
29. Drougia A, Giapros V, Krallis N, Theocharis P, Nikaki A, Tzoufi M, et al. Incidence and risk factors for cerebral palsy in infants with perinatal problems: a 15-year review. Early Hum Dev. 83:541–547. 2007.
Article
30. Einspieler C, Cioni G, Paolicelli PB, Bos AF, Dressler A, Ferrari F, et al. The early markers for later dyskinetic cerebral palsy are different from those for spastic cerebral palsy. Neuropediatrics. 33:73–78. 2002.
Article
31. EXPRESS Group, Fellman V, Hellström-Westas L, Norman M, Westgren M, Källén K, et al. One-year survival of extremely preterm infants after active perinatal care in Sweden. JAMA. 301:2225–2233. 2009.
Article
32. Gilard V, Chadie A, Ferracci FX, Brasseur-Daudruy M, Proust F, Marret S, et al. Post hemorrhagic hydrocephalus and neurodevelopmental outcomes in a context of neonatal intraventricular hemorrhage: an institutional experience in 122 preterm children. BMC Pediatrics. 18:288. 2018.
Article
33. Gilliaux M, Renders A, Dispa D, Holvoet D, Sapin J, Dehez B, et al. Upper limb robot-assisted therapy in cerebral palsy: a single-blind randomized controlled trial. Neurorehabil Neural Repair. 29:183–192. 2015.
34. Gormley ME Jr. Treatment of neuromuscular and musculoskeletal problems in cerebral palsy. Pediatr Rehabil. 4:5–16. 2001.
Article
35. Gotardo JW, Volkmer NFV, Stangler GP, Dornelles AD, Bohrer BBA, Carvalho CG. Impact of peri-intraventricular haemorrhage and periventricular leukomalacia in the neurodevelopment of preterms: a systematic review and meta-analysis. PLoS One. 14:e0223427. 2019.
36. Graham HK. Painful hip dislocation in cerebral palsy. Lancet. 359:907–908. 2002.
Article
37. Graham HK, Thomason P, Willoughby K, Hastings-Ison T, Stralen RV, Dala-Ali B, et al. Musculoskeletal pathology in cerebral palsy: a classification system and reliability study. Children (Basel). 8:252. 2021.
Article
38. Haataja L, Mercuri E, Guzzetta A, Rutherford M, Counsell S, Flavia Frisone M, et al. Neurologic examination in infants with hypoxicischemic encephalopathy at age 9 to 14 months: use of optimality scores and correlation with magnetic resonance imaging findings. J Pediatr. 138:332–337. 2001.
Article
39. Hadders-Algra M, Groothuis AM. Quality of general movements in infancy is related to neurological dysfunction, adhd, and aggressive behaviour. Dev Med Child Neurol. 41:381–391. 1999.
Article
40. Han JH, Shin JE, Lee SM, Eun HS, Park MS, Park KI. Hearing impairments in preterm infants: factors associated with discrepancies between screening and confirmatory test results. Neonatal Med. 27:126–132. 2020.
Article
41. Hanna SE, Rosenbaum PL, Bartlett DJ, Palisano RJ, Walter SD, Avery L, et al. Stability and decline in gross motor function among children and youth with cerebral palsy aged 2 to 21 years. Dev Med Child Neurol. 51:295–302. 2009.
Article
42. Hinson HE, Hanley DF, Ziai WC. Management of intraventricular hemorrhage. Curr Neurol Neurosci Rep. 10:73–82. 2010.
Article
43. Hirvonen M, Ojala R, Korhonen P, Haataja P, Eriksson K, Gissler M, et al. The incidence and risk factors of epilepsy in children born preterm: a nationwide register study. Epilepsy Res. 138:32–38. 2017.
Article
44. Hollebrandse NL, Spittle AJ, Burnett AC, Anderson PJ, Roberts G, Doyle LW, et al. School-age outcomes following intraventricular haemorrhage in infants born extremely preterm. Arch Dis Child Fetal Neonatal Ed. 106:4–8. 2021.
Article
45. Hollung SJ, Bakken IJ, Vik T, Lydersen S, Wiik R, Aaberg KM, et al. Comorbidities in cerebral palsy: a patient registry study. Dev Med Child Neurol. 62:97–103. 2020.
Article
46. Holwerda JC, Van Braeckel KNJA, Roze E, Hoving EW, Maathuis CGB, Brouwer OF, et al. Functional outcome at school age of neonatal posthemorrhagic ventricular dilatation. Early Hum Dev. 96:15–20. 2016.
Article
47. Hsu CL, Hung CL, Huang SJ, Yin CH, Chu CH, Kuo TJ, et al. Impact of rehabilitation intensity on 3-year mortality among children with moderate to severe cerebral palsy: a population-based cohort study. Int J Environ Res Public Health. 18:9932. 2021.
Article
48. Inder TE, Perlman JM, Volpe JJ : Chapter 24 - preterm intraventricular hemorrhage/posthemorrhagic hydrocephalus in Volpe JJ, Inder TE, Darras BT, de Vries LS, du Plessis AJ, Neil JJ, et al. (eds) : Volpe’s neurology of the newborn (sixth edition). Amsterdam : Elsevier, 2018, pp637-698.e621.
49. Katz-Leurer M, Rotem H, Keren O, Meyer S. The effects of a ‘homebased’ task-oriented exercise programme on motor and balance performance in children with spastic cerebral palsy and severe traumatic brain injury. Clin Rehabil. 23:714–724. 2009.
Article
50. Kerr Graham H, Selber P. Musculoskeletal aspects of cerebral palsy. J Bone Joint Surg Br. 85:157–166. 2003.
51. Kulkarni AV, Shams I. Quality of life in children with hydrocephalus: results from the hospital for sick children, Toronto. J Neurosurg. 107(5 Suppl):358–364. 2007.
Article
52. Landry SH, Schmidt M, Richardson MA. The effects of intraventricular hemorrhage on functional communication skills in preterm toddlers. J Dev Behav Pediatr. 10:299–306. 1989.
Article
53. Larson EB, Feigon M, Gagliardo P, Dvorkin AY. Virtual reality and cognitive rehabilitation: a review of current outcome research. NeuroRehabilitation. 34:759–772. 2014.
Article
54. Lee JH, Youn Y, Chang YS. Short- and long-term outcomes of very low birth weight infants in korea: Korean neonatal network update in 2019. Clin Exp Pediatr. 63:284–290. 2020.
Article
55. Legge N, Lutz T, Wocadlo C, Rieger I. Long-term neurodevelopmental outcome in preterm infants with intraventricular haemorrhage. J Paediatr Child Health. 58:1797–1802. 2022.
Article
56. Li X, Kang Y, Tang H. The effects of early rehabilitation in high-risk infants with brain injury: a systematic review and meta-analysis. Transl Pediatr. 10:2467–2478. 2021.
Article
57. Limbrick DD Jr, de Vries LS. New insights into the management of posthemorrhagic hydrocephalus. Semin Perinatol. 46:151597. 2022.
Article
58. Luu TM, Ment LR, Schneider KC, Katz KH, Allan WC, Vohr BR. Lasting effects of preterm birth and neonatal brain hemorrhage at 12 years of age. Pediatrics. 123:1037–1044. 2009.
Article
59. Maggio MG, Maresca G, De Luca R, Stagnitti MC, Porcari B, Ferrera MC, et al. The growing use of virtual reality in cognitive rehabilitation: fact, fake or vision? A scoping review. J Natl Med Assoc. 111:457–463. 2019.
Article
60. Mansoor N, Solheim O, Fredriksli OA, Gulati S. Shunt complications and revisions in children: a retrospective single institution study. Brain Behav. 11:e2390. 2021.
Article
61. McLaughlin J, Bjornson K, Temkin N, Steinbok P, Wright V, Reiner A, et al. Selective dorsal rhizotomy: meta-analysis of three randomized controlled trials. Dev Med Child Neurol. 44:17–25. 2002.
Article
62. McPhee PG, Claridge EA, Noorduyn SG, Gorter JW. Cardiovascular disease and related risk factors in adults with cerebral palsy: a systematic review. Dev Med Child Neurol. 61:915–923. 2019.
Article
63. Morgan C, Crowle C, Goyen TA, Hardman C, Jackman M, Novak I, et al. Sensitivity and specificity of general movements assessment for diagnostic accuracy of detecting cerebral palsy early in an australian context. J Paediatr Child Health. 52:54–59. 2016.
Article
64. Morgan C, Darrah J, Gordon AM, Harbourne R, Spittle A, Johnson R, et al. Effectiveness of motor interventions in infants with cerebral palsy: a systematic review. Dev Med Child Neurol. 58:900–909. 2016.
Article
65. Morgan C, Novak I, Badawi N. Enriched environments and motor outcomes in cerebral palsy: systematic review and meta-analysis. Pediatrics. 132:e735–e746. 2013.
Article
66. Morrell DS, Pearson JM, Sauser DD. Progressive bone and joint abnormalities of the spine and lower extremities in cerebral palsy. Radiographics. 22:257–268. 2002.
Article
67. Movsas TZ, Pinto-Martin JA, Whitaker AH, Feldman JF, Lorenz JM, Korzeniewski SJ, et al. Autism spectrum disorder is associated with ventricular enlargement in a low birth weight population. J Pediatr. 163:73–78. 2013.
Article
68. Nithianantharajah J, Hannan AJ. Enriched environments, experiencedependent plasticity and disorders of the nervous system. Nat Rev Neurosci. 7:697–709. 2006.
Article
69. O’Connell NE, Smith KJ, Peterson MD, Ryan N, Liverani S, Anokye N, et al. Incidence of osteoarthritis, osteoporosis and inflammatory musculoskeletal diseases in adults with cerebral palsy: a population-based cohort study. Bone. 125:30–35. 2019.
Article
70. O’Keefe M, Kafil-Hussain N, Flitcroft I, Lanigan B. Ocular significance of intraventricular haemorrhage in premature infants. Br J Ophthalmol. 85:357–359. 2001.
Article
71. O’Shea TM, Allred EN, Kuban KC, Hirtz D, Specter B, Durfee S, et al. Intraventricular hemorrhage and developmental outcomes at 24 months of age in extremely preterm infants. J Child Neurol. 27:22–29. 2012.
Article
72. Özek E, Kersin SG. Intraventricular hemorrhage in preterm babies. Turk Pediatri Ars. 55:215–221. 2020.
73. Patra K, Wilson-Costello D, Taylor HG, Mercuri-Minich N, Hack M. Grades I-II intraventricular hemorrhage in extremely low birth weight infants: effects on neurodevelopment. J Pediatr. 149:169–173. 2006.
Article
74. Pavone V, Testa G, Restivo DA, Cannavò L, Condorelli G, Portinaro NM, et al. Botulinum toxin treatment for limb spasticity in childhood cerebral palsy. Front Pharmacol. 7:29. 2016.
Article
75. Peterson MD, Gordon PM, Hurvitz EA. Chronic disease risk among adults with cerebral palsy: the role of premature sarcopoenia, obesity and sedentary behaviour. Obes Rev. 14:171–182. 2013.
Article
76. Pinto C, Malik P, Desai R, Shelar V, Bekina-Sreenivasan D, Satnarine TA, et al. Post-hemorrhagic hydrocephalus and outcomes amongst neonates with intraventricular hemorrhage: a systematic review and pooled analysis. Cureus. 13:e18877. 2021.
Article
77. Prechtl HF, Einspieler C, Cioni G, Bos AF, Ferrari F, Sontheimer D. An early marker for neurological deficits after perinatal brain lesions. Lancet. 349:1361–1363. 1997.
Article
78. Radic JA, Vincer M, McNeely PD. Outcomes of intraventricular hemorrhage and posthemorrhagic hydrocephalus in a population-based cohort of very preterm infants born to residents of nova scotia from 1993 to 2010. J Neurosurg Pediatr. 15:580–588. 2015.
Article
79. Ramstad K, Jahnsen R, Skjeldal OH, Diseth TH. Characteristics of recurrent musculoskeletal pain in children with cerebral palsy aged 8 to 18 years. Dev Med Child Neurol. 53:1013–1018. 2011.
Article
80. Reidy N, Morgan A, Thompson DK, Inder TE, Doyle LW, Anderson PJ. Impaired language abilities and white matter abnormalities in children born very preterm and/or very low birth weight. J Pediatr. 162:719–724. 2013.
Article
81. Riquelme I, do Rosário RS, Vehmaskoski K, Natunen P, Montoya P. Influence of chronic pain in physical activity of children with cerebral palsy. NeuroRehabilitation. 43:113–123. 2018.
Article
82. Rohrer-Baumgartner N, Holthe IL, Svendsen EJ, Røe C, Egeland J, Borgen IMH, et al. Rehabilitation for children with chronic acquired brain injury in the child in context intervention (cici) study: study protocol for a randomized controlled trial. Trials. 23:169. 2022.
Article
83. Romeo DM, Ricci D, Brogna C, Mercuri E. Use of the hammersmith infant neurological examination in infants with cerebral palsy: a critical review of the literature. Dev Med Child Neurol. 58:240–245. 2016.
Article
84. Rosenbaum PL, Walter SD, Hanna SE, Palisano RJ, Russell DJ, Raina P, et al. Prognosis for gross motor function in cerebral palsy: creation of motor development curves. JAMA. 288:1357–1363. 2002.
Article
85. Sadowska M, Sarecka-Hujar B, Kopyta I. Cerebral palsy: current opinions on definition, epidemiology, risk factors, classification and treatment options. Neuropsychiatr Dis Treat. 16:1505–1518. 2020.
86. Saito N, Ebara S, Ohotsuka K, Kumeta H, Takaoka K. Natural history of scoliosis in spastic cerebral palsy. Lancet. 351:1687–1692. 1998.
Article
87. Salem Y, Godwin EM. Effects of task-oriented training on mobility function in children with cerebral palsy. NeuroRehabilitation. 24:307–313. 2009.
Article
88. Sherlock RL, Anderson PJ, Doyle LW; Victorian Infant Collaborative Study Group. Neurodevelopmental sequelae of intraventricular haemorrhage at 8 years of age in a regional cohort of elbw/very preterm infants. Early Hum Dev. 81:909–916. 2005.
Article
89. Siffel C, Kistler KD, Sarda SP. Global incidence of intraventricular hemorrhage among extremely preterm infants: a systematic literature review. J Perinat Med. 49:1017–1026. 2021.
Article
90. Skiöld B, Eriksson C, Eliasson AC, Adén U, Vollmer B. General movements and magnetic resonance imaging in the prediction of neuromotor outcome in children born extremely preterm. Early Hum Dev. 89:467–472. 2013.
Article
91. Sobana M, Halim D, Aviani JK, Gamayani U, Achmad TH. Neurodevelopmental outcomes after ventriculoperitoneal shunt placement in children with non-infectious hydrocephalus: a meta-analysis. Childs Nerv Syst. 37:1055–1065. 2021.
Article
92. Stavsky M, Mor O, Mastrolia SA, Greenbaum S, Than NG, Erez O. Cerebral palsy-trends in epidemiology and recent development in prenatal mechanisms of disease, treatment, and prevention. Front Pediatr. 5:21. 2017.
Article
93. Stoll BJ, Hansen NI, Bell EF, Shankaran S, Laptook AR, Walsh MC, et al. Neonatal outcomes of extremely preterm infants from the nichd neonatal research network. Pediatrics. 126:443–456. 2010.
Article
94. Thompson DK, Chen J, Beare R, Adamson CL, Ellis R, Ahmadzai ZM, et al. Structural connectivity relates to perinatal factors and functional impairment at 7years in children born very preterm. Neuroimage. 134:328–337. 2016.
Article
95. Tilton AH. Management of spasticity in children with cerebral palsy. Semin Pediatr Neurol. 11:58–65. 2004.
Article
96. Van Naarden Braun K, Doernberg N, Schieve L, Christensen D, Goodman A, Yeargin-Allsopp M. Birth prevalence of cerebral palsy: a populationbased study. Pediatrics. 137:1–9. 2016.
Article
97. van Praag H, Kempermann G, Gage FH. Neural consequences of environmental enrichment. Nat Rev Neurosci. 1:191–198. 2000.
98. Vohr BR, Garcia-Coll C, Mayfield S, Brann B, Shaul P, Oh W. Neurologic and developmental status related to the evolution of visual-motor abnormalities from birth to 2 years of age in preterm infants with intraventricular hemorrhage. J Pediatr. 115:296–302. 1989.
Article
99. Vohr BR, Wright LL, Dusick AM, Mele L, Verter J, Steichen JJ, et al. Neurodevelopmental and functional outcomes of extremely low birth weight infants in the national institute of child health and human development neonatal research network, 1993-1994. Pediatrics. 105:1216–1226. 2000.
Article
100. Vollmer B, Roth S, Riley K, Sellwood MW, Baudin J, Neville BG, et al. Neurodevelopmental outcome of preterm infants with ventricular dilatation with and without associated haemorrhage. Dev Med Child Neurol. 48:348–352. 2006.
Article
101. Whitaker AH, Feldman JF, Lorenz JM, McNicholas F, Fisher PW, Shen S, et al. Neonatal head ultrasound abnormalities in preterm infants and adolescent psychiatric disorders. Arch Gen Psychiatry. 68:742–752. 2011.
Article
102. Whitehead E, Dodds L, Joseph KS, Gordon KE, Wood E, Allen AC, et al. Relation of pregnancy and neonatal factors to subsequent development of childhood epilepsy: a population-based cohort study. Pediatrics. 117:1298–1306. 2006.
Article
103. Wroblewska-Seniuk K, Greczka G, Dabrowski P, Szyfter-Harris J, Mazela J. Hearing impairment in premature newborns-analysis based on the national hearing screening database in poland. PLoS One. 12:e0184359. 2017.
Article
104. Yazıcı M, Livanelioğlu A, Gücüyener K, Tekin L, Sümer E, Yakut Y. Effects of robotic rehabilitation on walking and balance in pediatric patients with hemiparetic cerebral palsy. Gait Posture. 70:397–402. 2019.
Article
105. Yim SY, Yang CY, Park JH, Kim MY, Shin YB, Kang EY, et al. Korean database of cerebral palsy: a report on characteristics of cerebral palsy in South Korea. Ann Rehabil Med. 41:638–649. 2017.
Article
106. Ziv I, Blackburn N, Rang M, Koreska J. Muscle growth in normal and spastic mice. Dev Med Child Neurol. 26:94–99. 1984.
Article
Full Text Links
  • JKNS
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr