J Korean Med Sci.  2023 Apr;38(15):e114. 10.3346/jkms.2023.38.e114.

Dysphagia Requiring Medical Attention in Parkinson’s Disease: A Korean Population-Based Study

• Cha S
• Chang WK
• Cho HM
• Han K
• Paik NJ
• Kwon S
• Kim WS

• KMID: 2541553
• DOI: http://doi.org/10.3346/jkms.2023.38.e114

Abstract

Background
Patients with Parkinson’s disease (PD) experience both motor and non-motor symptoms, including dysphagia. Although PD is closely associated with dysphagia, the prevalence or risk of dysphagia in PD is unclear, especially in Asian countries.
Methods
The prevalence of PD and dysphagia with PD in the general population was analyzed using the Korean National Health Insurance Service (NHIS) database. The prevalence per 100,000 persons of PD and dysphagia with PD from 2006 to 2015 was analyzed in the general population aged ≥ 40 years. Patients newly diagnosed with PD between 2010 and 2015 were compared with those without PD.
Results
The prevalence of PD and dysphagia in patients with PD increased continuously during the study period and was highest in the ninth decade of life. The percentage of patients with dysphagia in patients with PD increased with age. Patients with PD showed an adjusted hazard ratio of 3.132 (2.955–3.320) for dysphagia compared to those without PD.
Conclusion
This nationwide study showed increasing trends in the prevalence of PD and dysphagia among patients with PD in Korea between 2006 and 2015. The risk of dysphagia was three times higher in patients with PD than that in those without PD, highlighting the importance of providing particular attention.

Keyword

Dysphagia; Parkinson’s Disease; Hazard Ratio; Prevalence; Population-Based Study

Figure

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  Fig. 1 The prevalence (per 100,000 persons) of Parkinson’s disease (A) and Parkinson’s disease with dysphagia (B), and the percentage of patients with dysphagia among those with Parkinson’s disease (C) from 2006 to 2015. The prevalence (per 100,000 persons) of Parkinson’s disease (D) and Parkinson’s disease with dysphagia (E), and the percentage of patients with dysphagia among those with Parkinson’s disease (F) by age group.

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