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J Korean Diabetes.  2023 Mar;24(1):12-17. 10.4093/jkd.2023.24.1.12.

Diabetes and Cancer

Affiliations
  • 1Division of Endocrinology, Department of Internal Medicine, Ilsan Paik Hospital, Inje University College of Medicine, Goyang, Korea

Abstract

Diabetes mellitus and cancer are the most common life-threatening illnesses worldwide. Previous epidemiologic studies have suggested a strong association between increased risk of cancer and diabetes mellitus. Potential biological mechanisms underlying the relationship include obesity, hyperglycemia, hyperinsulinemia, chronic inflammation, and oxidative stress. The most common diabetes-related cancers are pancreatic cancer, hepatocellular cancer, breast cancer, endometrial cancer, and colorectal cancer. Special attention should be paid to diabetic patients using careful cancer screening and providing preventive anti-cancer strategies.

Keyword

Cancer; Diabetes mellitus; Screening
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