Korean J Fam Pract.  2023 Mar;13(1):63-66. 10.21215/kjfp.2023.13.1.63.

Reversible Neuropsychiatric Symptoms of Primary Hyperparathyroidism after Parathyroidectomy

• Shin HH
• Choi CJ

• KMID: 2540647
• DOI: http://doi.org/10.21215/kjfp.2023.13.1.63

Abstract

Primary hyperparathyroidism, mainly caused by parathyroid adenoma, is a disease in which most patients are asymptomatic and usually diagnosed incidentally by routine laboratory tests. Even if symptoms are present, they tend to be nonspecific, such as fatigue, irritability, and weakness, making primary hyperparathyroidism difficult to diagnose based only on symptoms. This case report describes a patient with parathyroid adenoma who visited the Department of Family Medicine with difficulty in describing her symptoms due to dominant neuropsychiatric symptoms. She had neuropsychiatric symptoms, such as lack of energy and concentration, foggy state, sleeplessness, nervousness, depressive symptoms, and multiple musculoskeletal pain. Hyperparathyroidism was difficult to diagnose based solely on a gibberish patient’s description of symptoms, and she was not aware that she had severe osteoporosis. Neuropsychiatric symptoms and multiple musculoskeletal pain improved after excision of the parathyroid adenoma.

Keyword

Hyperparathyroidism; Parathyroid Adenoma; Neuropsychiatric; Symptoms