Korean J Fam Pract.  2023 Mar;13(1):38-46. 10.21215/kjfp.2023.13.1.38.

Risk Assessment of Periodontitis according to Metabolic Score for Insulin Resistance in Korean Population: Korea National Health and Nutrition Examination Survey VI (2013–2015)

• Kim IH
• Lee YC
• Kwon YJ
• Lee YJ

• KMID: 2540644
• DOI: http://doi.org/10.21215/kjfp.2023.13.1.38

Abstract

Background
Studies have reported an association between periodontitis, a chronic inflammatory disease of the periodontal tissues, and insulin resistance. The Metabolic Score for Insulin Resistance (METS-IR) index was recently developed to assess insulin resistance. This study aimed to investigate the association between periodontitis and insulin resistance according to the METS-IR index.
Methods
A total of 10,807 participants from the 6th National Health and Nutrition Examination Survey (2013–2015) were included in this study. We defined periodontitis as the community periodontal index score of 3 or higher in at least one site. Multiple logistic regression analyses were conducted to calculate odds ratios (OR) and 95% confidence intervals (CI) for periodontitis according to METS-IR index quartiles.
Results
Compared to the lowest quartile (Q1), the OR (95% CI) for periodontitis were 1.61 (1.37–1.90) in the second quartile (Q2), 2.37 (2.03–2.77) in the third quartile (Q3), and 2.89 (2.45–3.41) in the highest quartile (Q4) of the unadjusted model. After the adjustment for confounders, compared to Q1, the OR (95% CI) for periodontitis was 1.15 (0.93–1.42) in Q2, 1.30 (1.04–1.62) in Q3, and 1.39 (1.09–1.77) in Q4.
Conclusion
Our study found that METS-IR index had a significant positive association with the prevalence of periodontitis.

Keyword

Periodontitis; Community Periodontal Index; Chronic Inflammation; Insulin Resistance; Metabolic Score for Insulin Resistance