Clin Mol Hepatol.  2023 Feb;29(Suppl):S220-S227. 10.3350/cmh.2022.0360.

Preventive strategy for nonalcoholic fatty liver disease-related hepatocellular carcinoma

Affiliations
  • 1Center for Liver and Pancreatobiliary Cancer, National Cancer Center, Goyang, Korea

Abstract

The incidence of hepatocellular carcinoma (HCC) associated with nonalcoholic fatty liver disease (NAFLD) has been increasing worldwide, including Asia. Most patients with NAFLD-related HCC are at a much-advanced stage and older age at the time of diagnosis than those with virus-related HCC because they have not undergone HCC surveillance. This review provides an overview of the mechanism of hepatocarcinogenesis in NAFLD, preventive strategies for NAFLDrelated HCC, and strategies for the surveillance of patients with NAFLD.

Keyword

Hepatocellular carcinoma; Nonalcoholic fatty liver disease; Surveillance; Prevention
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