Mood Emot.
2022 Mar;20(1):1-7. 10.35986/me.2022.20.1.1.
Pharmacogenetics in Psychotropic Drugs
- Affiliations
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- 1Department of Psychiatry, Haeundae Paik Hospital, Inje University College of Medicine, Busan, Korea
- 2Paik Institute for Clinical Research, Inje University, Busan, Korea
- 3Department of Health Science and Technology, Graduate School, Inje University, Busan, Korea
- KMID: 2538382
- DOI: http://doi.org/10.35986/me.2022.20.1.1
Abstract
- Pharmacogenetics is used in psychiatry to predict the effects and side effects of psychotropic drugs. As most mental disorders have complex causes and unpredictable outcomes, personalized treatment using pharmacogenomics would be a useful method. However, pharmacogenetic studies in psychiatry have yielded insignificant results thus far, making their clinical application extremely limited. Early testing, prediction of drug side effects, and drug compliance will be discussed as considerations for the effectiveness of the pharmacogenetic test in psychiatry. Although pharmacogenetic tests in psychiatry do not yet have high sensitivity and specificity, they may be useful in the future for predicting clinical prognosis or developing novel drug treatments. As a result, the authors summarized the current state and prospects of pharmacogenetics in psychiatry in this review.
