Pediatr Infect Vaccine.  2022 Aug;29(2):61-69. 10.14776/piv.2022.29.e12.

Clinical Manifestations, Epidemiologic Characteristics, and Disease Burden of the Coronavirus Disease-19 in Children Ages 5-11 Years Old

Affiliations
  • 1Department of Pediatrics, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, the Republic of Korea
  • 2Department of Pediatrics, Chung-Ang University Hospital, College of Medicine, Chung-Ang University, Seoul, the Republic of Korea
  • 3Department of Pediatrics, Korea University Anam Hospital, College of Medicine, Korea University, Seoul, the Republic of Korea

Abstract

Coronavirus disease 2019 (COVID-19) has been a global pandemic for over 2 years. During the Omicron (B.1.1.529) variant-predominant period in South Korea, confirmed cases among children and adolescents surged. This review found that, although younger children may be less susceptible to COVID-19 than adolescents, more research is needed on the role of children and adolescents in the disease’s spread. Detailed epidemiological information about the transmissibility of the novel severe acute respiratory syndrome coronavirus 2 (SARSCoV-2) strain in children and adolescents is currently scarce, and more research is needed on the role of children and adolescents in disease’s spread. There may be a difference in the proportion of cases with severe disease requiring hospitalization depending on the dominant mutant strain; however, COVID-19 generally presents with a mild-to-moderate course in children aged 5–11 years old.

Keyword

Child; Epidemiology; SARS-CoV-2
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