Pediatr Infect Vaccine.  2021 Apr;28(1):1-6. 10.14776/piv.2021.28.e3.

Coronavirus Disease 2019: Reasons for Better Clinical Course for Children Compared to Adults

• Kwak BO
• Kim DH

• KMID: 2515596
• DOI: http://doi.org/10.14776/piv.2021.28.e3

Abstract

There have been several reports on why the clinical course of coronavirus disease 2019 (COVID-19) in pediatric patients is milder than in adults. There are distinctive points in the immune system between children and adults, as well as in the angiotensin-converting enzyme 2 gene expression, the characteristics of the respiratory system, the effects of comorbidities and risk factors, and the effect of infection control. Even though children tend to have mild forms of COVID-19, this does not mean that we should not regard it as a matter of importance.

Keyword

Severe acute respiratory syndrome coronavirus 2; COVID-19; Child; Respiratory infections