Infect Chemother.  2022 Dec;54(4):781-786. 10.3947/ic.2022.0103.

Use of the Monoclonal Antibody Regdanvimab to Treat Patients Hospitalized with COVID-19: Real-World Data during the Delta Variant Predominance

• Kwak YG
• Song JE
• Kang J
• Kang J
• Kang HK
• Koo HK
• Park HK
• Choi SB
• Lee HP
• Lee MJ
• Kim BN

• KMID: 2537714
• DOI: http://doi.org/10.3947/ic.2022.0103

Abstract

Regdanvimab is the only monoclonal antibody available in Korea that targets severe acute respiratory syndrome coronavirus 2. We retrospectively evaluated the clinical characteristics of 374 adults hospitalized with coronavirus disease 2019 (COVID-19) who were treated with regdanvimab from September through December 2021. In total, 322 (86.1%) patients exhibited risk factors for disease progression. Most patients (91.4%) improved without additional treatment. No patient died or was transferred to intensive care. This study shows that regdanvimab prevented disease progression in high-risk patients with mild to moderate COVID-19 infections during Delta variant predominance.

Keyword

COVID-19; Regdanvimab; Delta variant