Int J Arrhythm.  2022 Dec;23(4):24. 10.1186/s42444-022-00075-x.

Clinical significance, challenges and limitations in using artificial intelligence for electrocardiography‑based diagnosis

Affiliations
  • 1Cardiac Electrophysiology Unit, Cardiovascular Analytics Group, Hong Kong, China
  • 2Tianjin Key Laboratory of Ionic‑Molecular Function of Cardiovascular Disease, Department of Cardiology, Tianjin Institute of Cardiology, Second Hospital of Tianjin Medical University, Tianjin 300211, China
  • 3Cardiovas‑ cular Research Center, Massachusetts General Hospital, Boston, MA, USA
  • 4Broad Institute, Massachusetts Institute of Technology, Cambridge, MA, USA
  • 5Department of Cardiology, Larnaca General Hospital, Inomenon Poli‑ tion Amerikis, Larnaca, Cyprus
  • 6Department of Basic and Clinical Sciences, University of Nicosia Medical School, 2414 Nicosia, Cyprus
  • 7Kent and Medway Medical School, Canterbury, UK

Abstract

Cardiovascular diseases are one of the leading global causes of mortality. Currently, clinicians rely on their own analyses or automated analyses of the electrocardiogram (ECG) to obtain a diagnosis. However, both approaches can only include a finite number of predictors and are unable to execute complex analyses. Artificial intelligence (AI) has enabled the introduction of machine and deep learning algorithms to compensate for the existing limitations of cur‑ rent ECG analysis methods, with promising results. However, it should be prudent to recognize that these algorithms also associated with their own unique set of challenges and limitations, such as professional liability, systematic bias, surveillance, cybersecurity, as well as technical and logistical challenges. This review aims to increase familiarity with and awareness of AI algorithms used in ECG diagnosis, and to ultimately inform the interested stakeholders on their potential utility in addressing present clinical challenges.

Keyword

Electrocardiography; Artificial intelligence; Machine learning; Deep learning; Cardiovascular diseases
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