Ann Clin Microbiol.
2022 Dec;25(4):145-153. 10.5145/ACM.2022.25.4.4.
Antimicrobial Resistance Patterns of Acinetobacter baumannii and Pseudomonas aeruginosa Isolated From Vulnerable Patients in Korea, 2021
- Affiliations
-
- 1Department of Laboratory Medicine, National Health Insurance Service Ilsan Hospital, Goyang, Korea
- 2Department of Laboratory Medicine, Yonsei University College of Medicine, Seoul, Korea
- 3Research Institute of Bacterial Resistance, Yonsei University College of Medicine, Seoul, Korea
- 4Department of Laboratory Medicine, Chonnam National University Medical School, Gwangju, Korea
- 5Department of Laboratory Medicine, Chungbuk National University College of Medicine, Cheongju, Korea
- 6Department of Laboratory Medicine and Paik Institute for Clinical Research, Inje University College of Medicine, Busan, Korea
- 7Department of Laboratory Medicine, Jeju National University College of Medicine, Jeju, Korea
- 8Department of Laboratory Medicine, Hallym University Dongtan Sacred Heart Hospital, Hallym University College of Medicine, Hwaseong, Korea
- 9Department of Laboratory Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea
- 10Department of Laboratory Medicine, Keimyung University School of Medicine, Daegu, Korea
- KMID: 2537135
- DOI: http://doi.org/10.5145/ACM.2022.25.4.4
Abstract
- Background
We compared the antimicrobial resistance rates (AMRs) of major glucose nonfermenting gram-negative bacilli, Acinetobacter baumannii and Pseudomonas aeruginosa, under different clinical conditions. The purpose of the study was to provide useful background data to set up infection control strategies for infection-vulnerable patients.
Methods
The AMRs of blood isolates were compared in various clinical conditions, using data from the Antimicrobial Resistance Surveillance System in Korea.
Results
A. baumannii blood isolates from patients with healthcare-associated infections, inpatients, or intensive care unit (ICU)-admitted patients consistently exhibited higher AMRs to most antimicrobials, except minocycline, tigecycline, and colistin, compared with those from patients with community-acquired infections, outpatients, or non-ICU-admitted patients, respectively. P. aeruginosa blood isolates from patients with healthcare-associated infections showed higher AMRs to most antimicrobials, except ceftazidime and aztreonam, compared with those from patients with community-acquired infections, but not compared to those from inpatients or ICU-admitted patients.
Conclusion
Higher AMRs were associated with A. baumannii bloodstream infections under various clinical conditions, such as healthcare-associated infections and infections in inpatients and ICU-admitted patients. Considering the high AMRs and the limited number of treatment options of A. baumannii, vigorous efforts should be used to prevent the spreading of A. baumannii infections in patients with vulnerable conditions.
- Full Text Links
-
- Actions
-
Cited
- CITED
-
- Close
- Share
-
- Similar articles
-
- Antimicrobial Resistance and Clones of Acinetobacter Species and Pseudomonas aeruginosa
- Prevalence of Metallo-beta-lactamases in Imipenem-non-susceptible Pseudomonas aeruginosa and Acinetobacter baumannii
- Anti-inflammatory and Anti-bacterial Effects of Aloe vera MAP against Multidrug-resistant Bacteria
- Antimicrobial Therapy for Infections Caused by Carbapenem-Resistant Gram-Negative Bacteria
- Susceptibility of Clinical Isolates of Acinetobacter baumannii and Pseudomonas aeruginosa to Colistin and Polymyxin B in Korea
