Korean J Fam Pract.  2022 Dec;12(5):367-374. 10.21215/kjfp.2022.12.5.367.

Relationship between Sleep Duration and Insulin Resistance in Non-Diabetic Korean Adults: The Korea National Health and Nutrition Examination Survey, 2019–2020

• Park S
• Choi CJ

• KMID: 2536833
• DOI: http://doi.org/10.21215/kjfp.2022.12.5.367

Abstract

Background
Several recent studies demonstrated that inadequate sleep duration increases the risk of various chronic diseases such as type 2 diabetes, obesity, and metabolic syndrome. Therefore, the importance of sleep duration and quality is always emphasized, but as modern society becomes increasingly industrialized, the average sleep time is gradually decreasing. This study evaluated the relationship between sleep duration and insulin resistance.
Methods
This cross-sectional study included 7,646 Korean adults (3,402 male, 4,244 female) aged 19–64 years who participated in the Korean National Health and Nutrition Examination Survey, 2019–2020. Subjects were categorized into three groups (≤6, 6–8, or ≥8 h/day) based on self-reported sleep duration. We used the homeostatic model assessment of insulin resistance as an indicator of insulin resistance. The association between sleep duration and insulin resistance was investigated using general linear model and multivariable logistic regression analyses.
Results
In male, a short sleep duration (≤6 h) was associated with insulin resistance (odds ratio [OR], 1.287; 95% confidence interval [CI], 1.066-1.553) compared to an adequate sleep duration (6–8 h) after adjusting for age, sex, education, income, employment, mariatal status, smoking, drinking and physical activity. In female, a long sleep duration (≥8 h) showed a higher odds ratio for insulin resistance only in the unadjusted model (OR, 1.258; 95% CI, 1.001–1.580).
Conclusion
An inadequate sleep duration was significantly associated with insulin resistance.

Keyword

Sleep Deprivation; Insulin Resistance; Adult