Korean J Otorhinolaryngol-Head Neck Surg.  2022 Nov;65(11):727-733. 10.3342/kjorl-hns.2022.00703.

A Case of Extranodal Natural Killer/T Cell Lymphoma Combined With Actinomycosis

• Kim JS
• An TH
• Yeo NK

• KMID: 2536190
• DOI: http://doi.org/10.3342/kjorl-hns.2022.00703

Abstract

Actinomycosis is a rare anaerobic, gram-positive bacterial infection caused by Actinomyces. As an infection site for the disease, the cervicofacial area is common but the nasal cavity and the nasopharynx are rare. Actinomycosis causes chronic purulent granulomatous infection and is characterized by extensive infiltration, necrosis, and bone destruction on CT. Extranodal natural killer/T cell (NK/T cell) lymphoma, nasal type is more common in East Asia than elsewhere, comprising up to 7%-10% of all non-Hodgkin’s lymphoma. Early nasal symptoms are nonspecific and similar to chronic rhinosinusitis, such as nasal obstruction and nasal bleeding. With disease progression, inflammation and necrosis of the mucosa increase. We experienced a case of extranodal NK/T cell lymphoma in a 60-year-old female, who was diagnosed with opportunistic infection of actinomycosis. We report this case with a review of literature.

Keyword

Actinomycosis; Lymphoma, extranodal NK-T-cell; Nasal cavity