Korean J Transplant.  2022 Nov;36(Supple 1):S196. 10.4285/ATW2022.F-3302.

The difference of outcomes according to the duration of delayed graft function for kidney transplantation: 15-year experience of single institution

• Moon KY
• Park SC
• Yun SS

• KMID: 2535712
• DOI: http://doi.org/10.4285/ATW2022.F-3302

Abstract

Background
It is well known that delayed graft function (DGF) has an adverse effect on graft kidney. However, there are not many studies on the effect of DGF on the long-term prognosis of kidney transplantation and even fewer studies with subdivided DGF by period. So, we aimed to evaluate the outcome of DGF with its duration.
Methods
We retrospectively analyzed 1,904 patients who received kidney transplantation from 2005 to 2020 at Seoul St. Marys hospital. After performing propensity score matching by the presence of DGF, graft survival rates were analyzed according to the duration of DGF. DGF duration was subdivded into four groups. (A, no DGF; B, DGF days 0–1; C, DGF days 2–7; D, DGF days 8–13; E, DGF days 14–).
Results
DGFs were occurred in 84 (5%) patients. Among them, 10 (1.1%) patients were after living donor kidney transplantation and 74 (14.7%) patients were after deceased donor kidney transplantation. The 10-year graft survival of all DGF patients was 59.4%. When DGF duration was subdivided and compared, 10-year graft survival was A, 73.5%; B, 66.2%; C, 76.4%; D, 64.6%; E, 27.2% respectively, and there were significant differences between groups (log-rank P-value=0.01).
Conclusions
It was found that not only the presence of DGF but also its duration affects graft survival, and the worse prognosis can be predicted with longer duration of DGF.