Clin Exp Vaccine Res.  2022 Sep;11(3):298-301. 10.7774/cevr.2022.11.3.298.

Livedo reticularis following administration of ChAdOx1 nCoV-19 vaccine (AZD1222): a report of two cases

• Kim JH
• Uh JA
• Kim HS
• Lee SK
• Kim MS
• Lee UH

• KMID: 2534920
• DOI: http://doi.org/10.7774/cevr.2022.11.3.298

Abstract

The cutaneous appearance of transient or persistent livedo reticularis is characterized by violaceous, mottled, ring-shaped interconnecting lesions that form a reticular or net-like pattern. It can occur physiologically in response to cold exposure, such as in cutis marmorata, but can also be induced by pathological conditions such as vascular obliterans or venodilation. We report two cases of livedo reticularis that occurred on the lower limbs of two patients post ChAdOx1 nCoV-19 vaccination. As the patients had no other likely causes of livedo reticularis, the reticular skin lesions were suspected to occur in association with the ChAdOx1 nCoV-19 vaccination. Livedo reticularis is an uncommon adverse reaction, with few cases being reported post ChAdOx1 nCoV-19 vaccination.

Keyword

ChAdOx1 nCoV-19; Livedo reticularis; Vaccine; Case report