Neurospine.
2022 Sep;19(3):689-702. 10.14245/ns.2244616.308.
Surgical Considerations to Improve Recovery in Acute Spinal Cord Injury
- Tabarestani TQ
1 - Lewis NE2
- Kelly-Hedrick M1
- Zhang N3
- Cellini BR3
- Marrotte EJ4
- Williamson T5,6
- Wang H7
- Laskowitz DT7
- Faw TD2,8
- Abd-El-Barr MM9
- Affiliations
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- 1School of Medicine, Duke University, Durham, NC, USA
- 2Doctor of Physical Therapy Division, Department of Orthopaedic Surgery, Duke University, Durham, NC, USA
- 3Department of Psychology and Neuroscience, Trinity College of Arts and Sciences, Duke University, Durham, NC, USA
- 4Department of Neurology, Wake Forest University School of Medicine, Winston-Salem, NC, USA
- 5Department of Neurosurgery, Massachusetts General Hospital, Boston, MA, USA
- 6Center for Bioethics, Harvard Medical School, Boston, MA, USA
- 7Department of Neurology, Duke University, Durham, NC, USA
- 8Duke Institute for Brain Sciences, Duke University, Durham, NC, USA
- 9Department of Neurosurgery, Duke University, Durham, NC, USA
- KMID: 2533796
- DOI: http://doi.org/10.14245/ns.2244616.308
Abstract
- Acute traumatic spinal cord injury (SCI) can be a devastating and costly event for individuals, their families, and the health system as a whole. Prognosis is heavily dependent on the physical extent of the injury and the severity of neurological dysfunction. If not treated urgently, individuals can suffer exacerbated secondary injury cascades that may increase tissue injury and limit recovery. Initial recognition and rapid treatment of acute SCI are vital to limiting secondary injury, reducing morbidity, and providing the best chance of functional recovery. This article aims to review the pathophysiology of SCI and the most up-to-date management of the acute traumatic SCI, specifically examining the modern approaches to surgical treatments along with the ethical limitations of research in this field.
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