Med Lasers.  2022 Jun;11(2):78-83. 10.25289/ML.2022.11.2.78.

Effects of low-level laser therapy on utricular hair cell regeneration: a review of the efficacy of available treatment parameters

• Cuenca JP

• KMID: 2533575
• DOI: http://doi.org/10.25289/ML.2022.11.2.78

Abstract

Low-level laser therapy (LLLT) for vestibular treatments need further development in the sense to be used in clinical applications. One hurdle of LLLT on vestibular treatment studies is the lack of relevant parameters other researchers can reference for further studies. In this paper, we would like to provide laser parameters that are currently used in different body parts which may prove effective on vestibular hair cell regeneration at the cellular level. Following relevant parameters for laser therapy, some irradiation techniques provide protective mechanisms against ototoxic damage. The following review includes the possible mechanisms of LLLT which promote cellular and tissue regeneration capabilities with promising results. These treatments may be of use in potentially mitigating functional decline under optimized irradiation conditions. This review focused on, but is not limited to, the availability of 633 nm and 808 nm LLLT administration. These treatments provide therapeutic results in different structures under in vitro, in vivo, or ex vivo conditions. The relevant findings on the use of LLLT show similar effects of irradiation regardless of the designated area of interest. This data suggests the possibilities of using similar or modified parameters of LLLT within the vestibular organs.

Keyword

Low-level laser therapy; Photobiomodulation; Utricle; Vestibular hair cells