Anat Cell Biol.  2022 Sep;55(3):376-379. 10.5115/acb.22.048.

A rare additional lobe of cerebellum, projecting from its superior surface

Affiliations
  • 1Division of Anatomy, Department of Basic Medical Sciences, Manipal Academy of Higher Education, Manipal, India
  • 2Department of Anatomy, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, India

Abstract

Human cerebellum plays a vital role in motor coordination, regulation of muscle tone and maintaining the equilibrium of the body. It seldom shows anatomical/morphological variations. Herein, we report the presence of a small additional lobe projecting out on the superior surface of the right cerebellar hemisphere in the para-vermal area in an adult male cadaver. There was a notch on the tentorial surface of the occipital lobe of the right cerebral hemisphere, corresponding to the additional lobe of cerebellum. The additional lobe was histologically normal, with no evidence of any tumour cells. Knowledge of this variation is of importance to radiologists, neuroanatomists and neurosurgeons.

Keyword

Cerebellar; Brain; Coordination; Variation; Ataxia

Figure

  • Fig. 1 Posterior view of the brain showing the AL of the cerebellum. Occipital lobes have been pulled up slightly. LOL, left occipital lobe; ROL, right occipital lobe; LCH, left cerebellar hemisphere; RCH, right cerebellar hemisphere; V, vermis; AL, additional lobe.

  • Fig. 2 Closer view of the cerebellum showing the AL. LCH, left cerebellar hemisphere; RCH, right cerebellar hemisphere; V, vermis; AL, additional lobe.

  • Fig. 3 Photomicrograph of AL with H&E stain, showing normal histological features (10× magnification). ML, molecular layer; PN, purkinje neurons; GL, granular layer; WM, white matter.


Reference

References

1. Roostaei T, Nazeri A, Sahraian MA, Minagar A. 2014; The human cerebellum: a review of physiologic neuroanatomy. Neurol Clin. 32:859–69. DOI: 10.1016/j.ncl.2014.07.013. PMID: 25439284.
2. Van Essen DC, Donahue CJ, Glasser MF. 2018; Development and evolution of cerebral and cerebellar cortex. Brain Behav Evol. 91:158–69. DOI: 10.1159/000489943. PMID: 30099464. PMCID: PMC6097530.
Article
3. Witter L, De Zeeuw CI. 2015; Regional functionality of the cerebellum. Curr Opin Neurobiol. 33:150–5. DOI: 10.1016/j.conb.2015.03.017. PMID: 25884963.
Article
4. Hawkes R. 2018; The ferdinando rossi memorial lecture: zones and stripes-pattern formation in the cerebellum. Cerebellum. 17:12–6. DOI: 10.1007/s12311-017-0887-0. PMID: 28965328.
Article
5. Standring S. 2016. Gray's anatomy: the anatomical basis of clinical practice. 41st ed. Elsevier;Philadelphia:
6. Ahmad T, Raybaud C, McNeely D, Khan N, Nadi M. 2019; Supernumerary cerebellar vermis: a unique cerebellar anomaly. Can J Neurol Sci. 46:255–7. DOI: 10.1017/cjn.2019.2.
Article
7. Jackson JM, Sadove AM, Weaver DD, Edwards MK, Bull MJ. 1990; Unilateral duplication of the cerebellar hemisphere and internal, middle, and external ear: a clinical case study. Plast Reconstr Surg. 86:550–3. DOI: 10.1097/00006534-199009000-00028. PMID: 2385673.
8. Hattapoğlu S, Hamidi C, Göya C, Çetinçakmak MG, Teke M, Ekici F. 2015; A surprising case: a supernumerary heterotopic hemicerebellum. Clin Neuroradiol. 25:431–4. DOI: 10.1007/s00062-015-0371-5. PMID: 25622771.
Article
9. Agarwal S, Gathwala G. 2011; Third cerebellar hemisphere: an unusual new cerebellar anomaly. AJNR Am J Neuroradiol. 32:E73–4. DOI: 10.3174/ajnr.A2473. PMID: 21415147. PMCID: PMC7965887.
Article
10. Barkovich AJ. 1995. Pediatric neuroimaging. 2nd ed. Raven Press;New York: p. 246–57. DOI: 10.1007/s00062-015-0371-5.
11. Friede RL. 1989. Developmental neuropathology. 2nd ed. Springer-Verlag;Berlin: p. 361–71. DOI: 10.1007/978-3-642-73697-1_29.
12. Haldipur P, Dang D, Millen KJ. 2018; Embryology. Handb Clin Neurol. 154:29–44. DOI: 10.1016/B978-0-444-63956-1.00002-3. PMID: 29903446. PMCID: PMC6231496.
Article
13. Cho KH, Rodríguez-Vázquez JF, Kim JH, Abe H, Murakami G, Cho BH. 2011; Early fetal development of the human cerebellum. Surg Radiol Anat. 33:523–30. DOI: 10.1007/s00276-011-0796-8. PMID: 21380713.
Article
14. Chung SH, Kim CT, Jung YH, Lee NS, Jeong YG. 2010; Early cerebellar granule cell migration in the mouse embryonic development. Anat Cell Biol. 43:86–95. DOI: 10.5115/acb.2010.43.1.86. PMID: 21190009. PMCID: PMC2998778.
Article
Full Text Links
  • ACB
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr