Clin Endosc.  2022 Sep;55(5):581-587. 10.5946/ce.2021.283.

New sedatives and analgesic drugs for gastrointestinal endoscopic procedures

Affiliations
  • 1Department of Internal Medicine, Korea University Anam Hospital, Seoul, Korea
  • 2Department of Internal Medicine, Ewha Womans University Seoul Hospital, Seoul, Korea
  • 3Department of Internal Medicine, Kangwon National University Hospital, Kangwon National University School of Medicine, Chuncheon, Korea
  • 4Department of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea
  • 5Department of Internal Medicine and Digestive Disease Center, Seoul Medical Center, Seoul, Korea
  • 6Department of Internal Medicine and Research Institute of Clinical Medicine of Jeonbuk National University-Biomedical Research Institute of Jeonbuk National University Hospital, Jeonju, Korea
  • 7Department of Pediatrics, Seoul Metropolitan Children’s Hospital, Seoul, Korea
  • 8Department of Internal Medicine, Wonkwang University Hospital, Wonkwang University School of Medicine, Iksan, Korea
  • 9Department of Internal Medicine, Gachon University Gil Medical Center, Incheon, Korea
  • 10Department of Internal Medicine, Uijeongbu St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Uijeongbu, Korea
  • 11Department of Internal Medicine, Dongguk University Ilsan Hospital, Goyang, Korea
  • 12Department of Internal Medicine, Incheon St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Incheon, Korea

Abstract

Procedural sedation has become increasingly common in endoscopy. Sedatives and analgesics induce anxiolysis and amnesia. In addition, an appropriate level of sedation is necessary for safe procedures including therapeutic endoscopy. Midazolam and propofol are the most commonly used drugs in sedative endoscopy. In recent years, the need to ascertain the safety and effectiveness of sedation has increased in practice. Therefore, new sedatives and analgesic drugs for optimal sedative endoscopy, have recently emerged. This article reviews the characteristics of sedatives and analgesics, and describes their clinical use in gastrointestinal endoscopy.

Keyword

Analgesics; Conscious sedation; Endoscopy; Hypnotics and sedatives

Cited by  1 articles

Development of a predictive model for hypoxia due to sedatives in gastrointestinal endoscopy: a prospective clinical study in Korea
Jung Wan Choe, Jong Jin Hyun, Seong-Jin Son, Seung-Hak Lee
Clin Endosc. 2024;57(4):476-485.    doi: 10.5946/ce.2023.198.


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