Clin Exp Otorhinolaryngol.  2022 Aug;15(3):283-291. 10.21053/ceo.2021.02285.

Comparative Study of Gasless Transaxillary, Bilateral Axillo-Breast, Unilateral Axillo-Breast With Carbon Dioxide Insufflation, Retroauricular, and Transoral Vestibular Endoscopic Thyroidectomy Approaches at a Single Institution: A Retrospective Analysis and Lessons Learned

Affiliations
  • 1Department of Otorhinolaryngology-Head and Neck Surgery, Korea Cancer Center Hospital, Korea Institute of Radiological and Medical Sciences (KIRAMS), Seoul, Korea
  • 2Department of Otolaryngology-Head and Neck Surgery, Center for Thyroid Cancer, National Cancer Center, Goyang, Korea

Abstract


Objectives
. This study aimed to present our experiences with various approaches for endoscopic thyroidectomy (ET) and to offer lessons for choosing an approach.
Methods
. The medical records of 701 patients who underwent ET via the transaxillary (TA), bilateral axillo-breast (BABA), unilateral axillo-breast with carbon dioxide insufflation (UABA), retroauricular (RA), or transoral vestibular (TO) approach between May 2008 and March 2020 were retrospectively reviewed. Postoperative pain and cosmetic outcomes were evaluated using visual analog scales.
Results
. The mean operative time of UABA was the shortest among the five approaches (TA, 194.65±51.13 minutes; BABA, 189.11±61.53 minutes; UABA, 118.62±30.23 minutes; RA, 168.22±45.63 minutes; TO, 196.10±40.19 minutes; P=0.02). BABA was the most painful approach, while TO was the least painful on postoperative day 1 (TA, 3.09±0.96; BABA, 3.59±0.92; UABA, 2.39±0.54; RA, 3.49±0.93; TO, 2.01±0.37; P=0.04) and day 3 (TA, 2.10±0.77; BABA, 2.59±0.88; UABA, 1.84±0.37; RA, 3.01±0.67; TO, 1.49±0.45; P=0.04). The TO group had the best cosmetic outcomes at 3 months (TA, 3.91±1.21; BABA, 4.52±1.13; UABA, 4.49±0.74; RA, 4.28±0.74; TO, 4.81±0.48; P=0.04).
Conclusion
. We present a single-surgeon experience of five distinctive ET approaches and the lessons from each approach, together with a literature review. This data may aid endoscopic thyroid surgeons in choosing from various ET approaches.

Keyword

Thyroidectomy; Thyroid Neoplasm; Carcinoma; Endoscopy

Figure

  • Fig. 1. Schematic drawings of various endoscopic thyroidectomy approaches. (A) Bilateral axillo-breast approach. (B) Gasless unilateral axillobreast approach. (C) Unilateral axillo-breast approach with CO2 insufflation. (D) Retroauricular approach. (E) Transoral vestibular approach with CO2 insufflation.

  • Fig. 2. Lip asymmetry shown after the transoral endoscopic thyroidectomy vestibular approach at postoperative 1 month in each affected patient (A, B).


Reference

1. Koh YW, Kim JW, Lee SW, Choi EC. Endoscopic thyroidectomy via a unilateral axillo-breast approach without gas insufflation for unilateral benign thyroid lesions. Surg Endosc. 2009; Sep. 23(9):2053–60.
2. Choe JH, Kim SW, Chung KW, Park KS, Han W, Noh DY, et al. Endoscopic thyroidectomy using a new bilateral axillo-breast approach. World J Surg. 2007; Mar. 31(3):601–6.
3. Ohgami M, Ishii S, Arisawa Y, Ohmori T, Noga K, Furukawa T, et al. Scarless endoscopic thyroidectomy: breast approach for better cosmesis. Surg Laparosc Endosc Percutan Tech. 2000; Feb. 10(1):1–4.
4. Lee MC, Mo JA, Choi IJ, Lee BC, Lee GH. New endoscopic thyroidectomy via a unilateral axillo-breast approach with gas insufflation: preliminary report. Head Neck. 2013; Apr. 35(4):471–6.
5. Terris DJ, Singer MC, Seybt MW. Robotic facelift thyroidectomy: patient selection and technical considerations. Surg Laparosc Endosc Percutan Tech. 2011; Aug. 21(4):237–42.
6. Anuwong A. Transoral endoscopic thyroidectomy vestibular approach: a series of the first 60 human cases. World J Surg. 2016; Mar. 40(3):491–7.
7. Clark MP, Qayed ES, Kooby DA, Maithel SK, Willingham FF. Natural orifice translumenal endoscopic surgery in humans: a review. Minim Invasive Surg. 2012; 2012:189296.
8. Inabnet WB 3rd. Robotic thyroidectomy: must we drive a luxury sedan to arrive at our destination safely. Thyroid. 2012; Oct. 22(10):988–90.
9. Patel D, Kebebew E. Pros and cons of robotic transaxillary thyroidectomy. Thyroid. 2012; Oct. 22(10):984–5.
10. Perrier ND. Why I have abandoned robot-assisted transaxillary thyroid surgery. Surgery. 2012; Dec. 152(6):1025–6.
11. Tae K. Complications of transoral thyroidectomy: overview and update. Clin Exp Otorhinolaryngol. 2021; May. 14(2):169–78.
12. Anuwong A, Ketwong K, Jitpratoom P, Sasanakietkul T, Duh QY. Safety and outcomes of the transoral endoscopic thyroidectomy vestibular approach. JAMA Surg. 2018; Jan. 153(1):21–7.
13. Shan L, Liu J. A systemic review of transoral thyroidectomy. Surg Laparosc Endosc Percutan Tech. 2018; Jun. 28(3):135–8.
14. Nakajo A, Arima H, Hirata M, Mizoguchi T, Kijima Y, Mori S, et al. Trans-oral video-assisted neck surgery (TOVANS): a new transoral technique of endoscopic thyroidectomy with gasless premandible approach. Surg Endosc. 2013; Apr. 27(4):1105–10.
15. Park D, Kim HY, Kim HK, You JY, Dionigi G, Russell JO, et al. Institutional experience of 200 consecutive papillary thyroid carcinoma patients in transoral robotic thyroidectomy surgeries. Head Neck. 2020; Aug. 42(8):2106–14.
16. Kim KN, Lee DW, Kim JY, Han KH, Tae K. Carbon dioxide embolism during transoral robotic thyroidectomy: a case report. Head Neck. 2018; Mar. 40(3):E25–8.
17. Lee MC, Park H, Choi IJ, Lee BC, Lee GH. Comparative study of a gasless transaxillary approach versus a bilateral axillo-breast approach for endoscopic thyroidectomy in a single institute. Head Neck. 2014; May. 36(5):702–8.
18. Lee DW, Ko SH, Song CM, Ji YB, Kim JK, Tae K. Comparison of postoperative cosmesis in transaxillary, postauricular facelift, and conventional transcervical thyroidectomy. Surg Endosc. 2020; Aug. 34(8):3388–97.
19. Kim WS, Hong HJ, Shin YS, Choi EC, Choi HS, Koh YW. Increasing the size limit of benign thyroid lesions resectable by endoscopic thyroidectomy via a unilateral axillo-breast approach without gas insufflation. World J Surg. 2011; Oct. 35(10):2203–11.
20. Sun HX, Gao HJ, Ying XY, Chen X, Li QY, Qiu WH, et al. Robotic thyroidectomy via bilateral axillo-breast approach: experience and learning curve through initial 220 cases. Asian J Surg. 2020; Mar. 43(3):482–7.
21. Lee KE, Choi JY, Youn YK. Bilateral axillo-breast approach robotic thyroidectomy. Surg Laparosc Endosc Percutan Tech. 2011; Aug. 21(4):230–6.
22. Elzahaby IA, Fathi A, Abdelwahab K, Eldamshiety O, Metwally IH, Abdallah A, et al. Endoscopic thyroidectomy using the unilateral axillo-breast approach versus the modified anterior chest wall approach: a prospective comparative study. Surg Laparosc Endosc Percutan Tech. 2018; Dec. 28(6):366–70.
23. Ryu CH, Seok J, Jung YS, Ryu J. Novel robot-assisted thyroidectomy by a transaxillary gas-insufflation approach (TAGA): a preliminary report. Gland Surg. 2020; Oct. 9(5):1267–77.
24. Byeon HK, Holsinger FC, Tufano RP, Chung HJ, Kim WS, Koh YW, et al. Robotic total thyroidectomy with modified radical neck dissection via unilateral retroauricular approach. Ann Surg Oncol. 2014; Nov. 21(12):3872–5.
25. Lee DW, Bang HS, Jeong JH, Kwak SG, Choi YY, Tae K. Cosmetic outcomes after transoral robotic thyroidectomy: comparison with transaxillary, postauricular, and conventional approaches. Oral Oncol. 2021; Mar. 114:105139.
26. Luna-Ortiz K, Gomez-Pedraza A, Anuwong A. Lessons learned from the transoral endoscopic thyroidectomy with vestibular approach (TOETVA) for the treatment of thyroid carcinoma. Ann Surg Oncol. 2020; May. 27(5):1356–60.
27. Park JO, Anuwong A, Kim MR, Sun DI, Kim MS. Transoral endoscopic thyroid surgery in a Korean population. Surg Endosc. 2019; Jul. 33(7):2104–13.
28. Park JO, Park YJ, Kim MR, Sun DI, Kim MS, Koh YW. Gasless transoral endoscopic thyroidectomy vestibular approach (gasless TOETVA). Surg Endosc. 2019; Sep. 33(9):3034–9.
29. Tae K, Ji YB, Song CM, Ryu J. Robotic and endoscopic thyroid surgery: evolution and advances. Clin Exp Otorhinolaryngol. 2019; Feb. 12(1):1–11.
30. Sung ES, Ji YB, Song CM, Yun BR, Chung WS, Tae K. Robotic thyroidectomy: comparison of a postauricular facelift approach with a gasless unilateral axillary approach. Otolaryngol Head Neck Surg. 2016; Jun. 154(6):997–1004.
31. Nguyen HX, Nguyen LT, Nguyen HV, Nguyen HX, Trinh HL, Nguyen TX, et al. Comparison of transoral thyroidectomy vestibular approach and unilateral axillobreast approach for endoscopic thyroidectomy: a prospective cohort study. J Laparoendosc Adv Surg Tech A. 2021; Jan. 31(1):11–7.
32. Lee DY, Oh DJ, Kang KR, Kim MS, Oh KH, Baek SK, et al. Comparison of learning curves for retroauricular and transaxillary endoscopic hemithyroidectomy. Ann Surg Oncol. 2016; Nov. 23(12):4023–8.
33. Liang TJ, Wang NY, Tsai CY, Liu SI, Chen IS. Outcome comparison between endoscopic transoral and bilateral axillo-breast approach thyroidectomy performed by a single surgeon. World J Surg. 2021; Jun. 45(6):1779–84.
34. Lee J, Lee JH, Nah KY, Soh EY, Chung WY. Comparison of endoscopic and robotic thyroidectomy. Ann Surg Oncol. 2011; May. 18(5):1439–46.
35. Razavi CR, Vasiliou E, Tufano RP, Russell JO. Learning curve for transoral endoscopic thyroid lobectomy. Otolaryngol Head Neck Surg. 2018; Oct. 159(4):625–9.
36. Draaijers LJ, Tempelman FR, Botman YA, Tuinebreijer WE, Middelkoop E, Kreis RW, et al. The patient and observer scar assessment scale: a reliable and feasible tool for scar evaluation. Plast Reconstr Surg. 2004; Jun. 113(7):1960–7.
37. Tae K. Transoral robotic thyroidectomy using the da Vinci single-port surgical system. Gland Surg. 2020; Jun. 9(3):614–6.
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