Clin Exp Otorhinolaryngol.  2022 Aug;15(3):254-263. 10.21053/ceo.2022.00248.

Aeroallergen Sensitization Status in South Korea From 2018 to 2021

• Kim I
• Minn D
• Kim S
• Kim JK
• Cho JH

• KMID: 2532989
• DOI: http://doi.org/10.21053/ceo.2022.00248

Abstract

Objectives
. Studies on the aeroallergen sensitization status of South Koreans based on large-scale data are lacking.
Methods
. We analyzed data from 368,156 multiple allergosorbent tests collected by a domestic medical diagnosis company from 3,735 hospitals nationwide from 2018 to 2021. We additionally collected sex, age, and regional data. If the level of an aeroallergen was 0.35 IU/mL or more, the test result for that aeroallergen was defined as positive, and positive cases were defined as those where one aeroallergen was positive. The positive ratio (PR) for aeroallergens was calculated using positive cases.
Results
. In total, 347,996 cases were analyzed, excluding cases with missing data. The percentage of positive cases was 56.7%, which was highest in adolescents (74.1%) and lowest in the elderly (47.0%). All four types of mites had high PRs (0.382–0.655), and mold had low PRs (0.023–0.058). Among pollens, the PRs of grasses were generally high (more than 0.14), followed by weeds (approximately 0.10), and the PRs of woods was less than 0.1. For animals, cats and dogs had the highest PRs, at 0.231 and 0.183, respectively. The value for cockroaches was also high, at 0.211. The PRs of indoor aeroallergens, such as mites, molds, and animals, were high in adolescents, and those of pollen and cockroaches were high in the elderly. In Jeju, the PR of Japanese cedars was extremely high (0.222).
Conclusion
. Koreans were found to be sensitized to a wide variety of aeroallergens. There were significant differences in sensitization patterns according to age and region.

Keyword

Aeroallergen; Sensitization; Multiple Allergosorbent Tests; Korea

Figure

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  Fig. 1. Regional distribution of cases. A: Seoul-Gyeonggi, B: Gangwon, C: Chungnam, D: Chungbuk, E: Jeonbuk, F: Jeonnam, G: Gyeongbuk, H: Gyeongnam, I: Jeju. The value in the parenthesis denotes the percentage of cases relative to the local population.

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  Fig. 2. Positive ratios of aeroallergens.

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  Fig. 3. Percentages of patients according to number of positive aeroallergen types.

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