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Impact of delayed graft function on clinical outcomes in highly sensitized patients after deceased-donor kidney transplantation

Kim SG, Hong S, Lee H, Eum SH, Kim YS, Jin K, Han S, Yang CW, Park WY, Chung BH

Background: We investigated whether the development of delayed graft function (DGF) in pre-sensitized patients affects the clinical outcomes after deceased-donor kidney transplantation (DDKT). Methods: The study included 709 kidney transplant recipients...
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Comparison of inhalant allergen sensitization between children, adolescents, and adults with asthma and allergic rhinitis

Lee NG, Kim HK, Choi GS

Purpose: Inhalant allergens are known as a major factor for respiratory allergic diseases. There are many differences in sensitization rates of inhalant allergens, depending on the environment and demographic factors....
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Changes in allergen sensitization in children with allergic diseases in the 1980 to 2019

Jung JH, Kim GE, Park M, Kim SY, Kim MJ, Lee YJ, Kim YH, Kim KW, Sohn MH

Purpose: Allergen sensitization is constantly changing, and understanding these changes can help manage and prevent allergic diseases. This research analyzed and compared the changes in allergen sensitization in children diagnosed...
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Heart Transplant Immunosuppression Strategies at Cedars-Sinai Medical Center

Chang DH, Youn JC, Dilibero D, Patel JK, Kobashigawa JA

Heart transplant is the optimal treatment for selected patients with end-stage heart failure. Immunosuppression after heart transplantation has significantly reduced the incidence of rejection and improved patient outcomes with the...
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Trends of Sensitization to Inhalant Allergens in Korean Children Over the Last 10 Years

Kim YJ, Lee MY, Yang AR, Sol IS, Kwak JH, Jung HL, Shim JW, Kim DS, Shim JY

Purpose: Climate and lifestyle changes increase an individual’s susceptibility to various allergens and also the incidence of allergic diseases. We aimed to examine the changes in sensitization rate for aeroallergens...
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Phenotypes of allergic diseases in children and their application in clinical situations

Lee E, Hong SJ

Allergic diseases, including allergic rhinitis, asthma, and atopic dermatitis, are common heterogeneous diseases that encompass diverse phenotypes and different pathogeneses. Phenotype studies of allergic diseases can facilitate the identification of...
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Limonene Inhibits Methamphetamine-Induced Sensitizations via the Regulation of Dopamine Receptor Supersensitivity

Gu SM, Kim SY, Lamichhane S, Hong JT, Yun J

Limonene is a cyclic terpene found in citrus essential oils and inhibits methamphetamine-induced locomotor activity. Drug dependence is a severe neuropsychiatric condition that depends in part on changes in neurotransmission...
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Desensitization in HLA Incompatible Transplantation

Park BG

In terminally ill patients, organ transplantation could be recommended as the treatment of choice. In Korea, living donor liver or kidney transplantation is much more frequent than deceased donor transplantation...
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Recent changing pattern of aeroallergen sensitization in children with allergic diseases: A single center study

Lee SJ, Kim JM, Kim HB

PURPOSE: Allergic diseases have been increasing worldwide over the past few decades. Allergic sensitization is a pivotal risk factor for the development of allergic diseases. The purpose of this study...
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Association between lead exposure and increased risk of bronchial asthma in Korean adolescents

Kang SY, Kim CK

PURPOSE: Several studies have reported an association between lead exposure and increased risk of allergic sensitization and asthma. According to the Centers for Disease Control and Prevention guidelines, An elevated...
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Aeroallergen sensitization and associated comorbid diseases of an adult Filipino population with allergic rhinitis

Navarro-Locsin CG, Lim-Jurado M

BACKGROUND: There is a large global variation in sensitization patterns to aeroallergens due to differences in climate, urbanization, and lifestyle. Knowledge of the most common inhalant allergens is important for...
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Etiology and clinical feature of oral allergy syndrome in children

Park YA, Jeong KU, Kim YH, Sol IS, Kim KW, Sohn MH, Lee SY, Kim KE

PURPOSE: Oral allergy syndrome (OAS) is a unique allergic reaction to fresh fruits or vegetables, which is caused by cross-reactivity between foods and pollens. This study was conducted to investigate...
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Case Report of Kidney Paired Donation (KPD) with Desensitization: the Strategy and Experience of 3-Way KPD in Samsung Medical Center

Oh D, Kang ES, Yu S, Chun K, Huh W, Jang HR, Cho CW, Lee N, Lee KW, Park H, Park JB, Kim SJ

As the need for the organ donation increases, strategies to increase kidney transplantation (KT) through expanded living donation have become essential. These include kidney paired donation (KPD) programs and desensitization...
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House Dust Mite Sensitization Is Inversely Associated with Plasma 25-Hydroxyvitamin D3 Levels in Patients with Severe Atopic Dermatitis

Jang YH, Sim HB, Moon SY, Lee WJ, Lee SJ, Jin M, Kim SH, Kim DW

BACKGROUND: The relationship between atopic dermatitis (AD) and low vitamin D levels has been studied. Emerging evidence has implicated vitamin D as a critical regulator of immunity, playing a role...
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Allergen sensitization and vitamin D status in young Korean children with urticaria

Lee JB, Lee SH, Han MY, Yoon JW

PURPOSE: Urticaria is a common disorder, with a lifetime incidence of approximately 15%–20% of the general population. It is difficult to differentiate urticaria in children because of the similarity in...
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Allergen sensitization and clinical characteristics in young children with atopic dermatitis

Na MS, Kim GR, Ha EK, Lee SJ, Sheen YH, Choi SH, Jung YH, Lee KS, Jee HM, Han MY

PURPOSE: Few studies have demonstrated the effects of aeroallergen sensitization on the development of atopic dermatitis (AD) in young children. This study aimed to investigate the sensitization rate of food...
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Fatal Invasive Pulmonary Aspergillosis after Combined Induction with Rituximab and Antithymocyte Globulin for Kidney Transplantation in a Sensitized Recipient, and Early Rejection Therapy with Plasmapheresis and Low-dose Immunoglobulin

Jeong DW, Lee SH, Moon JY, Kim YG, Lee YH, Kim K, Park H, Joo SH

A high degree of sensitization to human leukocyte antigen requires more intensive induction therapy; however, this increases vulnerability to opportunistic infections following kidney transplantation. Although recent studies have suggested that...
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The Abuse Potential of α-Piperidinopropiophenone (PIPP) and α-Piperidinopentiothiophenone (PIVT), Two New Synthetic Cathinones with Piperidine Ring Substituent

Botanas CJ, Yoon SS, de la Peña JB, dela Peña IJ, Kim M, Woo T, Seo JW, Jang CG, Park KT, Lee YH, Lee YS, Kim HJ, Cheong JH

A diversity of synthetic cathinones has flooded the recreational drug marketplace worldwide. This variety is often a response to legal control actions for one specific compound (e.g. methcathinone) which has...
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Allergen Sensitization Pattern by Sex: A Cluster Analysis in Korea

Ohn J, Paik SH, Doh EJ, Park HS, Yoon HS, Cho S

BACKGROUND: Allergens tend to sensitize simultaneously. Etiology of this phenomenon has been suggested to be allergen cross-reactivity or concurrent exposure. However, little is known about specific allergen sensitization patterns. OBJECTIVE: To...
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Patterns of Inhalant Allergen Sensitization and Geographical Variation in Korean Adults: A Multicenter Retrospective Study

Kang MG, Kim MY, Song WJ, Kim S, Jo EJ, Lee SE, Kwon JW, Lee SM, Park CS, Park HK, Park HW, Chang YS, Lee J, Lee YM, Jee YK, Lee JM, Choi IS, Cho SH

PURPOSE: Inhalant allergen sensitization is one of the major factors involved in the pathogenesis of allergic respiratory diseases. However, the sensitization is determined by interactions between genetic and environmental factors....
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