Korean Circ J.  2022 Sep;52(9):715-716. 10.4070/kcj.2022.0068.

Cardiac Sarcoidosis Mimicking Lymphoma in a Patient With Sjogren’s Syndrome

Affiliations
  • 1Department of Radiology, Faculty of Medicine, Kagawa University, Kagawa, Japan
  • 2Division of Hematology, Rheumatology and Respiratory Medicine, Department of Internal Medicine, Faculty of Medicine, Kagawa University, Kagawa, Japan


Figure

  • Figure 1 Cardiac sarcoidosis mimicking lymphoma. (A) Parasternal short-axis echocardiogram shows a low-echoic mass attached to the right ventricle free wall (arrow). (B and C) Axial ECG-gated CECT images show multiple masses with homogenous enhancement attached to the right ventricle free wall, interventricular septum and right atrium (arrows). (D) Gd-FST1WI in sagittal view shows multiple masses with homogenous enhancement (arrows). (E and F) Axial DWI and corresponding ADC map image reveal slightly diffusion restriction within the masses compared with myocardium (arrows). (G and H) Axial fused 18F-FDG PET/CT images show intense uptake in the cardiac masses. (I) 18F-FDG PET MIP image shows multiple avid uptakes in not only cardiac masses but also systemic enlarged lymph nodes. (J and K) low-power and high-power view of the lymph node revealed non-caseating epithelioid-cell granulomas and multinucleated giant cells (hematoxylin and eosin staining; J, ×100 and K, ×200).ADC = apparent diffusion coefficient; CECT = contrast enhanced computed tomography; DWI = diffusion weighted image; ECG = electrocardiogram; 18F-FDG = 18F-fluorodeoxyglucose; Gd-FST1WI = gadolinium-enhanced fat-suppressed T1-weighted image; MIP = maximum intensity projection; PET = positron emission tomography.


Reference

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2. Santiago T, Santiago M, Rovisco J, et al. Coexisting primary Sjögren’s syndrome and sarcoidosis: coincidence, mutually exclusive conditions or syndrome? Rheumatol Int. 2014; 34:1619–1622. PMID: 24770372.
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5. Shetty A, Carter JD. Sarcoidosis mimicking lymphoma on FDG-PET imaging. Radiol Case Rep. 2015; 6:409. PMID: 27307894.
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