Psychiatry Investig.
2022 Jul;19(7):588-594. 10.30773/pi.2022.0102.
Design and Methods of a Prospective Smartphone App-Based Study for Digital Phenotyping of Mood and Anxiety Symptoms Mixed With Centralized and Decentralized Research Form: The Search Your Mind (S.Y.M., 心) Project
- Affiliations
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- 1Chungnam National University College of Medicine, Daejeon, Republic of Korea
- 2Department of Psychiatry, Chungnam National University College of Medicine, Daejeon, Republic of Korea
- 3Department of Psychiatry, Chungnam National University Sejong Hospital, Sejong, Republic of Korea
- 4Department of Biomedical Systems Informatics, Yonsei University College of Medicine, Seoul, Republic of Korea
- 5Schulich School of Medicine and Dentistry, Western University, London, ON, Canada
- 6Department of Psychiatry, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada
- KMID: 2532058
- DOI: http://doi.org/10.30773/pi.2022.0102
Abstract
- In this study, the Search Your Mind (S.Y.M., 心) project aimed to collect prospective digital phenotypic data centered on mood and anxiety symptoms across psychiatric disorders through a smartphone application (app) platform while using both centralized and decentralized research designs: the centralized research design is a hybrid of a general prospective observational study and a digital platform-based study, and it includes face-to-face research such as informed written consent, clinical evaluation, and blood sampling. It also includes digital phenotypic assessment through an application-based platform using wearable devices. Meanwhile, the decentralized research design is a non-face-to-face study in which anonymous participants agree to electronic informed consent forms on the app. It also exclusively uses an application-based platform to acquire individualized digital phenotypic data. We expect to collect clinical, biological, and digital phenotypic data centered on mood and anxiety symptoms, and we propose a possible model of centralized and decentralized research design.
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