Korean J Otorhinolaryngol-Head Neck Surg.  2022 Jun;65(6):358-361. 10.3342/kjorl-hns.2021.00738.

A Case of Neuromyelitis Optica Spectrum Disorder of a Patient Who Present for Fungal Sinusitis

Affiliations
  • 1Department of Internal Medicine, Chosun University College of Medicine, Gwangju, Korea
  • 2Department of Otolaryngology-Head and Neck Surgery, Chosun University College of Medicine, Gwangju, Korea

Abstract

Neuromyelitis optica (NMO) is an inflammatory demyelinating disease of the central nervous system, characterized by repeatedly invading the brain, optic nerve, or spinal cord. In 2004, when a disease-specific antibody (aquaporin-4-immunoglobulin G) was discovered in the serum of an optic neuromyelitis patient, it was thought to be a separated disease from multiple sclerosis. Since 2004, however, the concept of the disease has been expanded to include NMO spectrum disorder (NMOSD). We experienced a rare case of NMOSD in a patient who presented with left visual disturbance and underwent endoscopic sinus surgery because of acute fungal sinusitis. We report this case with a review of the literature.

Keyword

Anti-aquaporin 4 autoantibody; Fungal; Neuromyelitis optica; Optic neuritis; Sinusitis
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