Korean J Blood Transfus.  2022 Apr;33(1):46-49. 10.17945/kjbt.2022.33.1.4 6.

Comparison between Screening Cells Including Di^a and Mi^a Antigen for Unexpected Antibody Screening

• Shin KH
• Kim HH
• Lee HJ
• Kim H

• KMID: 2529878
• DOI: http://doi.org/10.17945/kjbt.2022.33.1.4 6

Abstract

The Di^a and Mi^a antigens have been detected in Koreans with a frequency of 6.4∼14.5% and 0.9%, respectively. This study evaluated the effectiveness of different screening cells using the cells with Di^aand Mi^a antigens for unexpected antibody screening. An unexpected antibody-screening test was performed separately using different screening cells, including the Di^a antigen (Panel D) and Mi^a antigen (Panel M). A total of 2,077 specimens from 1,847 patients were collected, among which 49 (2.32%) and 43 (2.08%) were positive using Panel D and Panel M, respectively. Twenty-seven patients were positive with both panels, 2012 were negative with both panels, and thirty-eight patients showed a discordant result. The suspected anti-Di^aand anti-Mi^a were detected in 4 (0.19%) and 5 (0.24%) patients, respectively. Therefore, the frequency of anti-Di^a and anti-Mi^a antibodies in this study may be helpful for selecting unexpected antibody screening reagents.

Keyword

Diego; Miltenberg; Antibody screening