Ann Rehabil Med.  2022 Apr;46(2):60-70. 10.5535/arm.22036.

Rehabilitation of Individuals With Cancer

Affiliations
  • 1Department of Physical Medicine and Rehabilitation, Johns Hopkins University School of Medicine, Baltimore, MD, USA

Abstract

The survival rate of cancer is increasing as treatment improves. As patients with cancer now live longer, impairments may arise that impact quality of life (QOL) and function. Therefore, a focus on QOL is often as important as survival. An interdisciplinary team can achieve goal-oriented and patient-centered rehabilitation, which can optimize function and QOL, and minimize impairments, restrictions, and activity limitations. In most cases, cancer patients must be active participants in therapy and exhibit carryover. Patients with cancer often have impairments that include fatigue, pain, brain fog, impaired cognition, paresis, mood disorders, difficulty with activities of daily living (ADL), bowel/bladder/sexual dysfunction, and bone and soft tissue involvement. Adaptive equipment, exercise, and ADL training can mitigate restrictions on activity. The trajectory and phase of the disease along the continuum of cancer care may influence the goals of rehabilitation in that time window. QOL is often influenced by participation in vocational, recreational, and home-based activities. A holistic perspective should include an analysis of distress, socioeconomic barriers, and transportation limitations when addressing issues.

Keyword

Cancer; Rehababilitation; Lymphedema; Exercise programs

Figure

  • Fig. 1. Definitions of the integral role of rehabilitation for optimizing quality of life.

  • Fig. 2. Adaptive aides. From top to bottom, grabber, leg lifter, shoe horn, sponge stick.


Cited by  3 articles

Recent Trends in Rehabilitation for Cancer Patients
Kwan-Sik Seo
Ann Rehabil Med. 2022;46(3):111-113.    doi: 10.5535/arm.22072.

Cancer Rehabilitation Fact Sheet in Korea
Jin A Yoon, Bo Young Hong
Ann Rehabil Med. 2022;46(4):155-162.    doi: 10.5535/arm.22102.

Performance of Activities of Daily Living in Typically Developing Children in Korea: Normative Value of K-MBI
Mi-Jeong Yoon, Sungwoo Paek, Jongbin Lee, Youngdeok Hwang, Joon-Sung Kim, Yeun-Jie Yoo, Bo Young Hong
Ann Rehabil Med. 2024;48(4):281-288.    doi: 10.5535/arm.230040.


Reference

1. National Cancer Institute. NCI dictionary of cancer terms [Internet]. Washington, DC: National Cancer Institute. c2022 [cited 2022 Apr 15]. Available from: http://www.cancer.gov/dictionary.
2. World Health Organization. International classification of functioning, disability and health. Geneva, Switzerland: World Health Organization;2001. p. 1–25.
3. Santucci C, Carioli G, Bertuccio P, Malvezzi M, Pastorino U, Boffetta P, et al. Progress in cancer mortality, incidence, and survival: a global overview. Eur J Cancer Prev. 2020; 29:367–81.
Article
4. Jung KW, Won YJ, Kong HJ, Lee ES. Cancer statistics in Korea: incidence, mortality, survival, and prevalence in 2016. Cancer Res Treat. 2019; 51:417–30.
Article
5. Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, et al. Global Cancer Statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2021; 71:209–49.
Article
6. Keating NL, Norredam M, Landrum MB, Huskamp HA, Meara E. Physical and mental health status of older long-term cancer survivors. J Am Geriatr Soc. 2005; 53:2145–52.
Article
7. Grada AA, Phillips TJ. Lymphedema: pathophysiology and clinical manifestations. J Am Acad Dermatol. 2017; 77:1009–20.
8. Silver JK, Baima J, Mayer RS. Impairment-driven cancer rehabilitation: an essential component of quality care and survivorship. CA Cancer J Clin. 2013; 63:295–317.
Article
9. Stout NL, Binkley JM, Schmitz KH, Andrews K, Hayes SC, Campbell KL, et al. A prospective surveillance model for rehabilitation for women with breast cancer. Cancer. 2012; 118(8 Suppl):2191–200.
Article
10. Carli F, Silver JK, Feldman LS, McKee A, Gilman S, Gillis C, et al. Surgical prehabilitation in patients with cancer: state-of-the-science and recommendations for future research from a panel of subject matter experts. Phys Med Rehabil Clin N Am. 2017; 28:49–64.
11. Le Roy B, Pereira B, Bouteloup C, Costes F, Richard R, Selvy M, et al. Effect of prehabilitation in gastro-oesophageal adenocarcinoma: study protocol of a multicentric, randomised, control trial-the PREHAB study. BMJ Open. 2016; 6:e012876.
Article
12. Tjernstrom F, Fransson PA, Kahlon B, Karlberg M, Lindberg S, Siesjo P, et al. Vestibular PREHAB and gentamicin before schwannoma surgery may improve long-term postural function. J Neurol Neurosurg Psychiatry. 2009; 80:1254–60.
Article
13. Huang GH, Ismail H, Murnane A, Kim P, Riedel B. Structured exercise program prior to major cancer surgery improves cardiopulmonary fitness: a retrospective cohort study. Support Care Cancer. 2016; 24:2277–85.
Article
14. Cheville AL, Mustian K, Winters-Stone K, Zucker DS, Gamble GL, Alfano CM. Cancer rehabilitation: an overview of current need, delivery models, and levels of care. Phys Med Rehabil Clin N Am. 2017; 28:1–17.
15. Bruera E, Kim HN. Cancer pain. JAMA. 2003; 290:2476–9.
Article
16. Wang XS, Cleeland CS, Mendoza TR, Engstrom MC, Liu S, Xu G, et al. The effects of pain severity on healthrelated quality of life: a study of Chinese cancer patients. Cancer. 1999; 86:1848–55.
Article
17. Cella DF. Quality of life outcomes: measurement and validation. Oncology (Williston Park). 1996; 10(11 Suppl):233–46.
18. Mock V, Frangakis C, Davidson NE, Ropka ME, Pickett M, Poniatowski B, et al. Exercise manages fatigue during breast cancer treatment: a randomized controlled trial. Psychooncology. 2005; 14:464–77.
Article
19. Curt GA, Breitbart W, Cella D, Groopman JE, Horning SJ, Itri LM, et al. Impact of cancer-related fatigue on the lives of patients: new findings from the Fatigue Coalition. Oncologist. 2000; 5:353–60.
Article
20. Morrow GR, Shelke AR, Roscoe JA, Hickok JT, Mustian K. Management of cancer- related fatigue. Cancer Invest. 2005; 23:229–39.
21. Centeno C, Sanz A, Bruera E. Delirium in advanced cancer patients. Palliat Med. 2004; 18:184–94.
Article
22. Gagnon P, Allard P, Masse B, DeSerres M. Delirium in terminal cancer: a prospective study using daily screening, early diagnosis, and continuous monitoring. J Pain Symptom Manage. 2000; 19:412–26.
23. Fann JR, Roth-Roemer S, Burington BE, Katon WJ, Syrjala KL. Delirium in patients undergoing hematopoietic stem cell transplantation. Cancer. 2002; 95:1971–81.
Article
24. Gaudreau JD, Gagnon P, Harel F, Roy MA, Tremblay A. Psychoactive medications and risk of delirium in hospitalized cancer patients. J Clin Oncol. 2005; 23:6712–8.
Article
25. Braun IM, Rao SR, Pirl WF. Comparison of self-reported cognitive difficulties in a national sample of longterm cancer survivors and cancer-naïve controls. Psychosomatics. 2012; 53:68–74.
Article
26. McDaniel JS, Musselman DL, Porter MR, Reed DA, Nemeroff CB. Depression in patients with cancer. Diagnosis, biology, and treatment. Arch Gen Psychiatry. 1995; 52:89–99.
27. Alter CL, Pelcovitz D, Axelrod A, Goldenberg B, Harris H, Meyers B, et al. Identification of PTSD in cancer survivors. Psychosomatics. 1996; 37:137–43.
Article
28. O’Dell MW, Barr K, Spanier D, Warnick RE. Functional outcome of inpatient rehabilitation in persons with brain tumors. Arch Phys Med Rehabil. 1998; 79:1530–4.
Article
29. Kirshblum S, O’Dell MW, Ho C, Barr K. Rehabilitation of persons with central nervous system tumors. Cancer. 2001; 92(4 Suppl):1029–38.
Article
30. Eriks IE, Angenot EL, Lankhorst GJ. Epidural metastatic spinal cord compression: functional outcome and survival after inpatient rehabilitation. Spinal Cord. 2004; 42:235–9.
Article
31. Gilbert RW, Kim JH, Posner JB. Epidural spinal cord compression from metastatic tumor: diagnosis and treatment. Ann Neurol. 1978; 3:40–51.
Article
32. Gillespie MB, Brodsky MB, Day TA, Lee FS, Martin- Harris B. Swallowing-related quality of life after head and neck cancer treatment. Laryngoscope. 2004; 114:1362–7.
Article
33. Healey JH, Brown HK. Complications of bone metastases: surgical management. Cancer. 2000; 88(12 Suppl):2940–51.
34. Bunting RW, Shea B. Bone metastasis and rehabilita tion. Cancer. 2001; 92(4 Suppl):1020–8.
35. Bowman C, Piedalue KA, Baydoun M, Carlson LE. The quality of life and psychosocial implications of cancer- related lower-extremity lymphedema: a systematic review of the literature. J Clin Med. 2020; 9:3200.
Article
36. Ramos SM, O’Donnell LS, Knight G. Edema volume, not timing, is the key to success in lymphedema treatment. Am J Surg. 1999; 178:311–5.
Article
37. Schmitz KH, Ahmed RL, Troxel AB, Cheville A, Lewis- Grant L, Smith R, et al. Weight lifting for women at risk for breast cancer-related lymphedema: a randomized trial. JAMA. 2010; 304:2699–705.
Article
38. Stubblefield MD. Clinical evaluation and management of radiation fibrosis syndrome. Phys Med Rehabil Clin N Am. 2017; 28:89–100.
Article
39. Okunieff P, Augustine E, Hicks JE, Cornelison TL, Altemus RM, Naydich BG, et al. Pentoxifylline in the treatment of radiation-induced fibrosis. J Clin Oncol. 2004; 22:2207–13.
Article
40. Gillis TA, Donovan ES. Rehabilitation following bone marrow transplantation. Cancer. 2001; 92(4 Suppl):998–1007.
Article
41. Jonker-Pool G, van Basten JP, Hoekstra HJ, van Driel MF, Sleijfer DT, Koops HS, et al. Sexual functioning after treatment for testicular cancer: comparison of treatment modalities. Cancer. 1997; 80:454–64.
Article
42. Schover LR, Fouladi RT, Warneke CL, Neese L, Klein EA, Zippe C, et al. Defining sexual outcomes after treatment for localized prostate carcinoma. Cancer. 2002; 95:1773–85.
Article
43. Siegel K, Raveis VH, Houts P, Mor V. Caregiver burden and unmet patient needs. Cancer. 1991; 68:1131–40.
Article
44. Dumont S, Turgeon J, Allard P, Gagnon P, Charbonneau C, Vezina L. Caring for a loved one with advanced cancer: determinants of psychological distress in family caregivers. J Palliat Med. 2006; 9:912–21.
Article
45. Lee WT, Chan HF, Wong E. Improvement of feeding independence in end-stage cancer patients under palliative care: a prospective, uncontrolled study. Support Care Cancer. 2005; 13:1051–6.
Article
46. Burnham TR, Wilcox A. Effects of exercise on physiological and psychological variables in cancer survivors. Med Sci Sports Exerc. 2002; 34:1863–7.
Article
47. Holtzman J, Schmitz K, Babes G, Kane RL, Duval S, Wilt TJ, et al. Effectiveness of behavioral interventions to modify physical activity behaviors in general populations and cancer patients and survivors. Evid Rep Technol Assess (Summ). 2004; (102):1–8.
48. Dimeo FC, Thomas F, Raabe-Menssen C, Propper F, Mathias M. Effect of aerobic exercise and relaxation training on fatigue and physical performance of cancer patients after surgery. A randomised controlled trial. Support Care Cancer. 2004; 12:774–9.
Article
49. Thorsen L, Skovlund E, Stromme SB, Hornslien K, Dahl AA, Fossa SD. Effectiveness of physical activity on cardiorespiratory fitness and health-related quality of life in young and middle-aged cancer patients shortly after chemotherapy. J Clin Oncol. 2005; 23:2378–88.
Article
50. Redinbaugh EM, Baum A, Tarbell S, Arnold R. Endof- life caregiving: what helps family caregivers cope? J Palliat Med. 2003; 6:901–9.
51. Chen ML, Chu L, Chen HC. Impact of cancer patients’ quality of life on that of spouse caregivers. Support Care Cancer. 2004; 12:469–75.
Article
52. Short PF, Vargo MM. Responding to employment concerns of cancer survivors. J Clin Oncol. 2006; 24:5138–41.
Article
53. Spelten ER, Verbeek JH, Uitterhoeve AL, Ansink AC, van der Lelie J, de Reijke TM, et al. Cancer, fatigue and the return of patients to work-a prospective cohort study. Eur J Cancer. 2003; 39:1562–7.
Article
54. Torok S, Kokonyei G, Karolyi L, Ittzes A, Tomcsanyi T. Outcome effectiveness of therapeutic recreation camping program for adolescents living with cancer and diabetes. J Adolesc Health. 2006; 39:445–7.
Article
55. Mansky P, Sannes T, Wallerstedt D, Ge A, Ryan M, Johnson LL, et al. Tai chi chuan: mind-body practice or exercise intervention? Studying the benefit for cancer survivors. Integr Cancer Ther. 2006; 5:192–201.
Article
56. Galski T, Williams JB, Ehle HT. Effects of opioids on driving ability. J Pain Symptom Manage. 2000; 19:200–8.
Article
57. Lewis R, Patel B, Engle J. Cancer rehabilitation. In Gonzalez-Fernandez M, Schaaf S, editors. Handbook of physical medicine and rehabilitation. New York, NY: Springer Publishing Company;2022. p. 19–28.
Full Text Links
  • ARM
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr