Tuberc Respir Dis.  1982 Dec;29(4):205-212. 10.4046/trd.1982.29.4.205.

Immediate Effect of Cigarette Smoking on the Maximal Expiratory Flow-Volume Curve and Single Breath Nitrogen Washout Test

• KMID: 2528819
• DOI: http://doi.org/10.4046/trd.1982.29.4.205

Abstract

Pulmonary function test was performed on 30 healthy male subjects to study the immediate effect of cigarette smoking on the small airway obstruction. The subjects were all in the second and third decades and had no respiratory problems. Maximal expiratory flow-volume curve and single breath nitrogen washout test were performed before and after a cigarette smoking. Statistical analysis was done by “student paired t test". The results were summarized as follows; 1) After smoking, there were significant changes in the MEF₅₀, MEF_25-75, closing capacity/ total lung capacity, which are all effort independent part of lung fung test(p<0. 05). 2) There were no significant changes in the FVC, closing volume/vital capacity(p>0. 05). 3) FEV_1.0 and FEV_1.0/FVC also showed significant change(p<0. 05). But whether it was caused by true smoking effect or the subject’s fatigue resulting from repeated (3-6 times) forced expiratory efforts, still remains in question.