Oral Biol Res.  2022 Mar;46(1):1-9. 10.21851/obr.46.01.202203.1.

Maxillary sinus floor augmentation using two different ratios of cancellous and cortical freeze-dried bone allograft mixtures: clinical and histological outcomes

• Yang KI
• Ji CS
• Cho OH
• Yun HJ
• Lee WP
• Kim BO
• Yu SJ

• KMID: 2527535
• DOI: http://doi.org/10.21851/obr.46.01.202203.1

Abstract

The aim of this study was to evaluate the clinical and histologic outcomes of sinus floor augmentation using mixtures of cancellous and cortical freeze-dried bone allograft (AG) at two different ratios (5:5 and 3:7). The sinuses of 21 patients were grafted with the two types of mixed allografts. Cone-beam computerized tomography scans were obtained, and the radiographic parameters measured were residual bone height and bone gain after bone healing. Clinical examinations and histologic analyses were performed 6 months after the grafting procedure. Twenty implant sites in the 5:5 mixed AG group and 22 implant sites in the 3:7 mixed AG group were analyzed. The bone gain after bone healing was 13.0±3.1 mm in the 5:5 group and 14.5±3.5 mm in the 3:7 group. The survival rates of the implants in both groups were 100% during follow-up periods. The newly formed bone was 29.9±16.6% in the 5:5 AG group and 25.1±10.1% in the 3:7 AG group. Moreover, the percentage of residual graft material was 15.2±12.7% in the 5:5 AG group and 20.4±12.1% in the 3:7 AG group. The connective tissues were 55.0±14.0% and 54.6±10.0% in the 5:5 and 3:7 AG groups, respectively. The two different ratios of AG presented with different histological outcomes after bone healing. Additionally, adequate new bone formation for the placement of implants was achieved following maxillary sinus augmentation using both types of AG.

Keyword

Allograft; Bone regeneration; Bone substitutes; Clinical trial; Sinus floor augmentation