Arch Craniofac Surg.  2022 Feb;23(1):43-47. 10.7181/acfs.2022.00612.

Lacrimal sac lymphoma: a case report

• Ueathaweephol S
• Wongwattana P
• Chanlalit W
• Trongwongsa T
• Sutthinont S

• KMID: 2527107
• DOI: http://doi.org/10.7181/acfs.2022.00612

Abstract

Primary lymphoma originating from the lacrimal drainage system is a rare disease. Such lymphomas are mostly B-cell in origin and present nonspecific symptoms. The treatment of malignant lymphoma of the lacrimal drainage system is slightly different. We present the case of a 71-year-old woman with a painless mass below the medial canthus. Computed tomography (CT) scan of the orbit revealed a mass invading the right lacrimal sac. An incision biopsy was obtained, and the pathologic findings suggested a diagnosis of primary diffuse large B-cell lymphoma of the lacrimal sac. The patient was treated with chemotherapy and intrathecal methotrexate. After completing eight cycles of chemotherapy, the patient was followed up by a CT scan, which revealed nearly total resolution of an ill-defined enhancing mass. At the time of this case report writing, the patient is in complete remission at six months with no other complications.

Keyword

Case reports; Diffuse large B-cell lymphoma; Nasolacrimal sac; Lacrimal sac; Lymphoma