Korean J Dermatol.
2022 Feb;60(2):130-134.
Two Cases of Lymphomatoid Papulosis Mimicking Pseudolymphoma Successfully Treated with Low-Dose Methotrexate and 308-nm Ultraviolet Laser Therapy
- Affiliations
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- 1Department of Dermatology, Yonsei University Wonju College of Medicine, Wonju, Korea
Abstract
- Lymphomatoid papulosis (LyP) is a CD30＋ lymphoproliferative disorder characterized by chronic papulonodular eruptions. Highly potent topical steroids and phototherapy are the first-line modalities, and low-dose methotrexate (MTX) combined with folic acid is known to be safe and efficient for the treatment of LyP. However, there are concerns about whether whole-body phototherapy should be performed for limited lesions. Herein, we report the first case series of localized LyP mimicking pseudolymphoma successfully treated with low-dose MTX and 308 nm ultraviolet (UV) laser therapy. Clinicians should consider UV laser therapy as a novel treatment option because it has the advantage of selective treatment.
