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Tissue regeneration is one of the ultimate goals of maxillofacial surgery and various types of tissue engineering technologies have been utilized in clinics. Healthy resources of host cells and growth factors are essential for the tissue engineering, therefore autologous blood-derived cell therapy was introduced. In this article, clinical applications of the autologous platelet concentrates and stem cell separation therapy will be summarized and evaluated for their efficacy and feasibility in the current maxillofacial clinics.
Fig. 1
The layers after centrifugation, the blood components and separated cells are shown among PRP (platelet-rich plasma; the most left), PRF (platelet-rich fibrin; middle) and autologous bone marrow (BM) stem cell concentrate (the most right). The final product from each preparation method is written in blue.
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