Clin Exp Reprod Med.
2021 Dec;48(4):380-384. 10.5653/cerm.2021.04546.
Delayed postpartum regression of theca lutein cysts with maternal virilization: A case report
- Kim S
1 - Lee I1,2
- Park E3
- Rhee YJ1
- Kim K3
- Aljassim AI1,4
- Park JH2,5
- Lee JH2,6
- Yun BH1,2
- Seo SK1,2
- Cho S2,6
- Choi YS1,2
- Lee BS1,2
- Affiliations
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- 1Department of Obstetrics and Gynecology, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea
- 2Institute of Women’s Life Medical Science, Yonsei University College of Medicine, Seoul, Korea
- 3Department of Pathology, Yonsei University College of Medicine, Seoul, Korea
- 4Department of Obstetrics and Gynecology, King Faisal General Hospital, Al-Ahsa, Saudi Arabia
- 5Department of Obstetrics and Gynecology, Yongin Severance Hospital, Yonsei University College of Medicine, Seoul, Korea
- 6Department of Obstetrics and Gynecology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea
- KMID: 2524441
- DOI: http://doi.org/10.5653/cerm.2021.04546
Abstract
- Theca lutein cysts are rare, benign lesions responsible for gross cystic enlargement of both ovaries during pregnancy. This condition is also termed hyperreactio luteinalis. Elevated human chorionic gonadotropin (hCG) levels or states of hCG hypersensitivity seem to promote these changes, which in up to 30% of patients produce clinical signs of hyperandrogenism. Given the self-limiting course of theca lutein cysts, which are subject to spontaneous postpartum resolution, conservative treatment is the mainstay of patient management. Described herein is a rare case of theca lutein cysts with maternal virilization that failed to regress by 9 months after childbirth. Surgical intervention was eventually undertaken, necessitated by adnexal torsion.
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