J Korean Med Sci.  2022 Jan;37(2):e16. 10.3346/jkms.2022.37.e16.

Impact of Social Distancing on Intussusception Incidence in Children

• Choe YJ
• Lee Y
• Lee Y
• Shim JO

• KMID: 2524289
• DOI: http://doi.org/10.3346/jkms.2022.37.e16

Abstract

Following nonpharmaceutical intervention (NPI) to mitigate coronavirus disease 2019 has led to drastic reduction in incidence of communicable disease. Intussusception is commonly preceded by infectious pathogens. Indirect effect from NPI implementation on incidence of intussusception has not been understood fully. We conducted a cohort study to estimate the impact of NPI on incidence of intussusception in Korean children. The net risk ratio of intussusception incidence for 2020 compared to 2010–2019 was 0.53 (95% confidence interval [CI], 0.43–0.64) for boys and 0.56 (95% CI, 0.44–0.71) for girls (P for difference = 0.017). Our study showed an association between NPI implementation and reduction of intussusception incidence, with more profound reduction in boys compared to girls.

Keyword

Intussusception; Social Distancing; Non-pharmaceutical Intervention; COVID-19; Coronavirus

Figure

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  Fig. 1 Monthly incidence rates of intussusception in children aged < 5 years by sex, 2020 vs. 2010–2019, South Korea.CI = confidence interval.

Reference

1. Burnett E, Parashar UD, Tate JE. Associations of intussusception with adenovirus, rotavirus, and other pathogens: a review of the literature. Pediatr Infect Dis J. 2020; 39(12):1127–1130. PMID: 33060518.

2. Zheng J, Ye Y, Liao Y, Wang B. Fewer paediatric intussusception cases during the COVID-19 pandemic. J Paediatr Child Health. 2020; 56(7):1165.

3. Brown CM, Vostok J, Johnson H, Burns M, Gharpure R, Sami S, et al. Outbreak of SARS-CoV-2 infections, including COVID-19 vaccine breakthrough infections, associated with large public gatherings - Barnstable County, Massachusetts, July 2021. MMWR Morb Mortal Wkly Rep. 2021; 70(31):1059–1062. PMID: 34351882.

4. Park S, Michelow IC, Choe YJ. Trend of gastrointestinal infections following nonpharmaceutical interventions, South Korea, 2020. J Infect Dis. 2021; 224(2):368–371. PMID: 33963753.

5. Choi DH, Jung JY, Suh D, Choi JY, Lee SU, Choi YJ, et al. Impact of the COVID-19 outbreak on trends in emergency department utilization in children: a multicenter retrospective observational study in Seoul Metropolitan Area, Korea. J Korean Med Sci. 2021; 36(5):e44. PMID: 33527786.