.  2021 Dec;25(4):170-178. 10.32542/implantology.2021018.

Use of Porcine-derived Block Bone Substitutes for Guided Bone Regeneration in the Peri-implant Dehiscence Defects of the Mandibular Anterior Region

• Lee JH
• Jeong SN

• KMID: 2524043
• DOI: http://doi.org/10.32542/implantology.2021018

Abstract

Purpose
Various bone graf t materials are currently used for guided bone regeneration (GBR), but data are lacking on the superiority of one biomaterial relative to the other. In addition, achieving successf ul bone augmentation remains challenging. When used in GBR, block bone substitutes show better augmentation stability of the bone than particulated bone substitutes. Recently developed sof ttype block bone substitutes are widely used in clinical practice.
Materials and Methods
This study enrolled 12 patients who underwent implant placement with GBR in the mandibular anterior region between September 2016 and May 2021 in the Department of Periodontology, Daejeon Dental Hospital, Wonkwang University. GBR was performed using demineralized porcine bone mineral with 10% collagen (DPBM-C; LegoGraf t ^® ) and a resorbable collagen membrane (Bio-Gide ^® or Ossix Plus ^® ). The surgical site was sutured with 4-0 e-PTFE (Biotex ^® ) and 5-0 nylon (Monosof ^® ) by using modified horizontal mattress and interrupted suture methods. Stitch-out was perf ormed two weeks af ter the operation, and reentry surgery was performed within four to six months af ter the implant surgery.
Results
There was a significant decrease in bone thickness af ter five months of implant surgery with GBR compared with the decrease immediately af ter surgery. However, bone gains of more than 1.5 mm were observed at all measurement sites compared with those at baseline.
Conclusion
GBR perf ormed using demineralized porcine bone mineral with 10% collagen in combination with a resorbable collagen membrane is an effective and favorable treatment modality for peri-implant dehiscence defects in terms of clinical and radiographic outcomes during the healing period.

Keyword

Bone regeneration; Bone substitute; Cone-beam computed tomography; Dental implants; Wound healing