Korean J Sports Med.  2021 Dec;39(4):160-169. 10.5763/kjsm.2021.39.4.160.

Acute Effects of Postexercise Cigarette Smoking on Central Hemodynamics and Endothelial Function in Young Men

• Cho MJ
• Kim HJ
• Kim YW
• Bunsawat K
• Jae SY

• KMID: 2523231
• DOI: http://doi.org/10.5763/kjsm.2021.39.4.160

Abstract

Purpose
Recovery from exercise is a vulnerable phase that has been linked to increased susceptibility to sudden cardiovascular events. Cigarette smoking increases the risk of cardiovascular mortality and morbidity. We tested the hypothesis that postexercise cigarette smoking would attenuate hemodynamics and vascular function during recovery from exercise in young men.
Methods
Thirteen habitual smokers (age, 22±3 years; body mass index, 25.1±3.6 kg/m ² ) participated in (1) cigarette smoking (0.6 mg nicotine) and (2) sham smoking (SHAM) immediately postexercise (30 minutes on a treadmill; 40% to 60% of heart rate [HR] reserve) in a randomized order. Assessments were hemodynamics (HR, rate-pressure product [RPP], brachial and central artery blood pressures) and vascular function (arterial stiffness via carotid-femoral pulse wave velocity [PWV]; conduit vessel function via brachial artery flow-mediated dilation [FMD]). All variables were assessed at baseline, 10 minutes, and 30 minutes postexercise, except for FMD (baseline and 30 minutes postexercise).
Results
Compared with the SHAM trial, cigarette smoking increased HR, RPP, and brachial and central blood pressures postexercise (interaction, p＜ 0.05). PWV reduced and FMD increased postexercise in the SHAM trial, while cigarette smoking attenuated exercise-induced improvements (interaction, p＜ 0.05).
Conclusion
Cigarette smoking attenuated hemodynamic recovery and an improvement in arterial stiffness and conduit vessel function in young habitual smokers, thereby providing evidence for the negative effects of cigarette smoking during recovery from exercise.

Keyword

Tobacco; Postexercise; Vascular stiffness; Hemodynamics; Endothelial function

Figure

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  Fig. 1 Experimental design. HRR: heart rate reserve.

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  Fig. 2 Effects of postexercise cigarette smoking on (A) carotid-femoral pulse wave velocity (PWV) and (B) brachial artery flow-mediated dilation (FMD). Values are presented as mean±standard deviation. *p<0.05, different from baseline; †p< 0.05, different from the sham trial.

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