J Korean Med Sci.  2021 Nov;36(46):e317. 10.3346/jkms.2021.36.e317.

Trend of Antibiotic Use in Children with Acute Otitis Media in Korea

• Park KH
• Choe SA
• Shin JY
• Choe YJ

• KMID: 2522889
• DOI: http://doi.org/10.3346/jkms.2021.36.e317

Abstract

Public interventions have shown to optimize the use of antibiotics in children with acute otitis media (AOM). In this study, we describe the AOM-related antibiotic use among children in South Korea using national cohort data. We retrieved the Health Insurance Review & Assessment Service data to construct a national cohort of children aged 0–6 years who had been diagnosed with AOM between 2012 and 2018. Of 25,212,264 children included, the antibiotic prescription has increased for amoxicillin/amoxicillin-clavulanate from 56.1% in 2012 to 61.8% in 2018. Prescription has decreased for cephalosporin (35.1% in 2012 to 31.8% in 2018) and macrolide (8.7% in 2012 to 6.4% in 2018). National cohort data have shown an increased trend in AOM-related aminopenicillin prescription and downward trend cephalosporin and macrolide use in South Korea. A multi-faceted approach is required to control the antimicrobial resistance at a population level.

Keyword

Antibiotic; Otitis Media; Children; Korea

Figure

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  Fig. 1 Trend of antibiotic use for acute otitis media in children, Korean national cohort, 2012–2018.amoxiclav = amoxicillin-clavulanate.

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