Perinatology.
2021 Mar;32(1):27-30. 10.14734/PN.2021.32.1.27.
Congenital Acute Megakaryoblastic Leukemia in a Neonate with Antenatal Hepatosplenomegaly
- Affiliations
-
- 1Department of Pediatrics, College of Medicine, The Catholic University of Korea, Seoul, Korea
- 2Division of Hemato-oncology, Department of Pediatrics, Seoul St. Mary’s Hospital, Seoul, Korea
- 3Division of Neonatology, Department of Pediatrics, Seoul St. Mary’s Hospital, Seoul, Korea
- KMID: 2522510
- DOI: http://doi.org/10.14734/PN.2021.32.1.27
Abstract
- Various conditions can lead to antenatal hepatosplenomegaly. In addition to commonly known etiologies like hydrops fetalis or viral illnesses, hematologic disorders like congenital leukemia, although rare, should also be ruled out. We present a case of hepatosplenomegaly detected during antenatal screening in a neonate, in whom acute megakaryoblastic leukemia was diagnosed postnatally based on the immunophenotype.
